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GASTROESOPHAGEAL REFLUX DISEASE AND FUNCTIONAL DISORDERS OF THE BILIARY TRACT

https://doi.org/10.21886/2219-8075-2016-1-45-49

Abstract

Purpose: to determine the functional state of the biliary system at Gastroesophageal reflux disease (GERD) depending on the degree of esophageal mucosal lesions.

Material and methods: 115 patients with GERD were studied. Functional state of the biliary system was performed by dynamic ultrasound-based diagnostic medical imaging technique with using standard stimulus of gallbladder. Morphological study of the esophageal mucosa was done in all patients with GERD. The degree of inflammation was graduated according to the histological classification of reflux esophagitis F.Ismail-Beigi in the modification KLHeilmann

Results: different violations motor-evacuation function of the biliary system were detected in 89 (77.4%) patients with GERD: reduction of LP, as well as its prolongation, deferred primary reaction, gallbladder dyskinesia. Ultrasound signs of dysfunction the sphincter of Oddi were detected in 85 (73.9%) patients with GERD.

Summary: the positive relationship between reduced tone the sphincter of Oddi, which leads to erratic and excessive bile outflow in the duodenum, and the severity of GERD was revealed. Such relationship might be because of dysmotoric duodenum and duodeno-gastro-esophageal reflux, wherein alkaline contents of the reflux damage esophagus much more than gastric acidic contents.

About the Authors

N. G. Gravirovskaya
State Institution «Institute of Gastroenterology of NAMS of Ukraine», 96 pr. «Pravda», Dnipropetrovsk, Ukraine, 49074
Russian Federation


L. N. Mosiychuk
State Institution «Institute of Gastroenterology of NAMS of Ukraine», 96 pr. «Pravda», Dnipropetrovsk, Ukraine, 49074
Russian Federation


N. Yu. Oshmyanskaya
State Institution «Institute of Gastroenterology of NAMS of Ukraine», 96 pr. «Pravda», Dnipropetrovsk, Ukraine, 49074
Russian Federation


. .
State Institution «Institute of Gastroenterology of NAMS of Ukraine», 96 pr. «Pravda», Dnipropetrovsk, Ukraine, 49074
Russian Federation


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Review

For citations:


Gravirovskaya N.G., Mosiychuk L.N., Oshmyanskaya N.Yu., .  GASTROESOPHAGEAL REFLUX DISEASE AND FUNCTIONAL DISORDERS OF THE BILIARY TRACT. Medical Herald of the South of Russia. 2016;(1):45-49. (In Russ.) https://doi.org/10.21886/2219-8075-2016-1-45-49

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