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Detection of brucellosis markers in blood donations (clinical case reports)

https://doi.org/10.21886/2219-8075-2026-17-2-88-92

Abstract

Brucellosis is a systemic infectious zoonotic disease that tends to become chronic and is characterized by damage to the musculoskeletal, nervous, cardiovascular, genitourinary and other body systems. This article describes clinical cases of brucellosis infection in donors, incidentally identified as a result of blood donation. The primary cause of the disease in donors was infection with the brucellosis pathogen through alimentary and contact transmission. Blood donation is an important aspect of healthcare, ensuring patients’ access to essential blood components. Donated blood must undergo thorough laboratory testing before use to prevent the transmission of infectious diseases, including brucellosis. Ensuring the safety of transfusions is of paramount importance. The implementation of comprehensive control measures, including screening for brucellosis, is essential to prevent iatrogenic transmission of the pathogen and ensure the safety of recipients. The incidental detection of infection in donors indicates a lack of awareness of this disease and the need to improve current laboratory diagnostic protocols and preventive measures. This article substantiates the importance of implementing comprehensive clinical and laboratory monitoring of the donor population.

About the Authors

N. S. Sarkisyan
Stavropol Plague Control Research Institute
Russian Federation

Nushik S. Sarkisyan, Cand. Sci. (Med.), Head of the Department of Consulting and Preventive Work – Doctor of Clinical Laboratory Diagnostics

Stavropol


Competing Interests:

Authors declares no conflict of interest.



A. N. Kulichenko
Stavropol Plague Control Research Institute
Russian Federation

Aleksandr N. Kulichenko, Academician of the Russian Academy of Sciences, Dr. Sci. (Med.), Professor, Director

Stavropol


Competing Interests:

Authors declares no conflict of interest.



O. G. Golub
City Clinical Hospital No. 2 of Stavropol
Russian Federation

Olga G. Golub, head of the department for diagnosis, treatment and examination of occupational pathology of brucellosis, infectious disease doctor City Clinical Hospital No. 2

Stavropol


Competing Interests:

Authors declares no conflict of interest.



D. A. Gavrish
Stavropol Plague Control Research Institute
Russian Federation

Darya A. Gavrish, doctor of Clinical Laboratory Diagnostics, scientific and preventive clinical and diagnostic laboratory

Stavropol


Competing Interests:

Authors declares no conflict of interest.



References

1. Wang W, Liao Q, Wu X, Hou S, Wang Y, Wu J, Shen C, Chen S, Allain JP, Li C. Potential risk of blood transfusion-transmitted brucellosis in an endemic area of China. Transfusion. 2015;55(3):586-592. https://doi.org/10.1111/trf.12853

2. Gubanova M.N., Kopchenko T.G., Reznikova O.M., Madzaev S.R., Zhiburt E.B. Brucellosis: examination of blood donors in the Stavropol Territory. Transfusiology. 2017;3(18):37-43. (In Russ) eLIBRARY ID: 35426766 EDN: XWFBRJ


Review

For citations:


Sarkisyan N.S., Kulichenko A.N., Golub O.G., Gavrish D.A. Detection of brucellosis markers in blood donations (clinical case reports). Medical Herald of the South of Russia. 2026;17(2):88-92. (In Russ.) https://doi.org/10.21886/2219-8075-2026-17-2-88-92

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ISSN 2219-8075 (Print)
ISSN 2618-7876 (Online)