MECHANISMS OF FORMATION OF KIDNEY FIBROSIS BASED ON MICROVASCULAR LESIONS
https://doi.org/10.21886/2219-8075-2017-1-21-27
Abstract
The review deals with the description of the mechanisms involved in the formation of kidney fibrosis. Presented molecular factors activation of the pathological process, signaling pathways, competent cells with synthetic provospolitelnyh mediators, the role of epithelial-mesenchymal transition in the development and progression of renal fibrosis. Demonstrated evidence of the importance of the remodeling of the renal arteries of small diameter in the development and progression of renal fibrosis tissue. Sources of information on topics Review article full disclosure, a presentation of the current views on the study of this problem, use the database PubMed citations, RISC, Scopus, Web- Mathematical Sciences, Google Scholar, Copernicus index, Ulrich Periodicals Directory.
About the Author
E. S. Levitskaya
Rostov State Medical University
Russian Federation
29 Nakhichevanskiy st., Rostov-on-Don, 344022 Russia
Competing Interests: Конфликта интересов нет
Russian Federation
29 Nakhichevanskiy st., Rostov-on-Don, 344022 Russia
Competing Interests: Конфликта интересов нет
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Review
For citations:
Levitskaya E.S. MECHANISMS OF FORMATION OF KIDNEY FIBROSIS BASED ON MICROVASCULAR LESIONS. Medical Herald of the South of Russia. 2017;(1):21-27. (In Russ.) https://doi.org/10.21886/2219-8075-2017-1-21-27
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