FEATURES OF COOPERATION LYMPHOCYTE POPULATIONS IN THE DYNAMICS OF HIV INFECTION
https://doi.org/10.21886/2219-8075-2016-2-67-71
Abstract
Purpose: the determination of quantitative and functional parameters of T, B lymphocytes and natural killer cells in patients in the dynamics of HIV infection. Materials and methods: the immunophenotyping, reaction of blast transformation of lymphocytes, enzyme immunoassay were used in 50 HIV-infected patients. Clinical stage was determined in accordance with the classification of the CDC (1993). Results: the progression of HIV infection connected with impaired function of regulatory T-lymphocytes. B cells lost their ability to produce high-affinity antibodies in the dynamics of HIV infection. Summary: the innate immune cells retain their functional capacity at the same time.
About the Authors
L. P. Sizyakina
Rostov State Medical University,
29 Nakhichevansky st., Rostov-on-Don, 344022, Russia
Russian Federation
Russian Federation
I. I. Andreevа
Rostov State Medical University,
29 Nakhichevansky st., Rostov-on-Don, 344022, Russia
Russian Federation
Russian Federation
L. A. Kotieva
Rostov State Medical University,
29 Nakhichevansky st., Rostov-on-Don, 344022, Russia
Russian Federation
Russian Federation
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Review
For citations:
Sizyakina L.P., Andreevа I.I., Kotieva L.A. FEATURES OF COOPERATION LYMPHOCYTE POPULATIONS IN THE DYNAMICS OF HIV INFECTION. Medical Herald of the South of Russia. 2016;(2):67-71. (In Russ.) https://doi.org/10.21886/2219-8075-2016-2-67-71
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