THE INVERSION OF HOMEOSTATIC PROPERTIES OF THE IMMUNE SYSTEM IN PATIENTS WITH MULTIPLE SCLEROSIS
https://doi.org/10.21886/2219-8075-2016-2-23-27
Abstract
Purpose: the features of the innate and adaptive immunity of patients with multiple sclerosis was investigated. Materials and methods: the results of flow cytometry, reaction of blast transformation of lymphocytes,immunosorbent assay and other parameters of innate immunity of 85 patients with multiple sclerosis was investigated. Results: It is determined that the factors of innate immunity play a significant role in the pathogenesis of multiple sclerosis. We can see the evaluation of suchimmunogenesis stages as recognition, activation, proliferation, differentiation of immune cells. Summary: all stages of the immune response were disturbed during exacerbation of multiple sclerosis. The antigen recognition processes are restored with the remission of this disease. The stages of the activation, proliferation and differentiation of immune cells were without changes.
About the Authors
I. I. Andreevа
Rostov State Medical University,
29 Nakhichevansky st., Rostov-on-Don, 344022, Russia
Russian Federation
Russian Federation
L. P. Sizyakina
Rostov State Medical University,
29 Nakhichevansky st., Rostov-on-Don, 344022, Russia
Russian Federation
Russian Federation
Z. A. Goncharova
Rostov State Medical University,
29 Nakhichevansky st., Rostov-on-Don, 344022, Russia
Russian Federation
Russian Federation
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Review
For citations:
Andreevа I.I., Sizyakina L.P., Goncharova Z.A. THE INVERSION OF HOMEOSTATIC PROPERTIES OF THE IMMUNE SYSTEM IN PATIENTS WITH MULTIPLE SCLEROSIS. Medical Herald of the South of Russia. 2016;(2):23-27. (In Russ.) https://doi.org/10.21886/2219-8075-2016-2-23-27
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