THE INFLUENCE OF REMAXOL ON HOMOCYSTEINE METABOLISM IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
https://doi.org/10.21886/2219-8075-2015-2-25-27
Abstract
Purpose: study of Remaxol and Cytoflavin influence on homocysteine metabolism and creation of a method for correction of hyperhomocysteinemia development.
Materials and methods: we examined 58 patients with diagnosed acute myocardial infarction with ST segment elevation complicated with acute heart failure according to Killip classification (class II-III). The patients were subdivided in two groups: the first group received traditional intensive therapy while the second group additionally received Remaxol and Cytoflavin. We studied the condition of homocysteine metabolism in connection with various types of intensive care.
Results: we established that the first group even after seven days had homocysteine level consistently higher than in the control group while the second group by the seventh day demonstrated complete normalization of this essential ferment defining the development of endothelial dysfunction.
Summary: intensive therapy of acute myocardial infarction including Cytoflavin and Remaxol decreases the intensity of pathochemical reactions: development of oxidative stress, and completely normalizes homocysteine metabolism.
About the Authors
V. M. Zhenilo
Rostov State Medical University, Department of Anaesthesiology and Emergency Care
Russian Federation
Russian Federation
Z. T. Astakhova
Rostov State Medical University, Department of Anaesthesiology and Emergency Care
Russian Federation
Russian Federation
A. Z. Avsaragova
Rostov State Medical University, Department of Anaesthesiology and Emergency Care
Russian Federation
Russian Federation
M. V. Zhenilo
Rostov State Medical University, Department of Anaesthesiology and Emergency Care
Russian Federation
Russian Federation
A. J. Razin
Rostov State Medical University, Department of Anaesthesiology and Emergency Care
Russian Federation
Russian Federation
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Review
For citations:
Zhenilo V.M., Astakhova Z.T., Avsaragova A.Z., Zhenilo M.V., Razin A.J. THE INFLUENCE OF REMAXOL ON HOMOCYSTEINE METABOLISM IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION. Medical Herald of the South of Russia. 2015;(2):25-27. (In Russ.) https://doi.org/10.21886/2219-8075-2015-2-25-27
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