CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF EARLY STAGES OF HIV INFECTION IN CHILDREN INFECTED BY THE PARENTERAL ROUTE
https://doi.org/10.21886/2219-8075-2015-2-20-24
Abstract
Purpose: to give characteristic of clinical and immunological features of HIV infection initial stages in parenterally infected children.
Materials and methods: clinical and immunological examination of 100 parenterally HIV infected children to early stages of HIV infection are surveyed.
Results: after the incubation period (stage 1) the stage of primary manifestations 2 (2A in 54%, 2B – in 26%, 2B – in 20% patients), then latent stage 3 in patients developed. Speed of transition to secondary diseases stage 4 is associated with existence of antenatal and postnatal risk groups, HIV infection at chest age, against infectious disease, development and long current of stage 2B, early emergence of lymphoproliferativy and metabolic syndromes, decrease CD4+-lymphocytes count. In chest age HIV infected children, reduction of the incubation period, a heavy and long current of primary manifestations stage 2, fast accession of the HIV-associated symptoms, immunosupression progressing, reduction of latent stage 3 duration were noted.
Summary: research results revealed disease speed progressing factors in children and early stages feature associated with age at the time of HIV infection.
About the Authors
V. B. Denisenko
Rostov State Medical University, Department of Pediatric Infectious Diseases
Russian Federation
Russian Federation
A. N. Simovanyan
Rostov State Medical University, Department of Pediatric Infectious Diseases
Russian Federation
Russian Federation
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Review
For citations:
Denisenko V.B., Simovanyan A.N. CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF EARLY STAGES OF HIV INFECTION IN CHILDREN INFECTED BY THE PARENTERAL ROUTE. Medical Herald of the South of Russia. 2015;(2):20-24. (In Russ.) https://doi.org/10.21886/2219-8075-2015-2-20-24
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