CLINICAL AND EXPERIMENTAL BASIS OF OPHTHALMIC RESEARCH IN DIAGNOSTICS FORMS AND SEVERITY OF DIVERTICULAR DISEASE

Abstract

Purpose: clinical and experimental study in the diagnosis of ophthalmic forms and severity of diverticular disease Physiological and pathological research methods conducted.Materials and Methods: according to the original method (Russian Federation patent № 2087943) a model of diverticulosis of the colon was applied to 40 animals (rabbits). Animals were divided into 4 groups.At the clinic were examined 64 patients with diverticular disease, without comorbidity: local diverticulosis (17.2%), subtotal (57.7%), total (9.4%), and chronic complications (18.7%).All patients took a biochemical test (Russian Federation patent № 2119168)Results: in diverticular disease of the colon in 100% of cases, violations of the visual analyzer are detected, due to violation of local hemodynamics, as well as the activation of the lipid peroxidation (LPO).Proved the effectiveness of ophthalmic examination in the diagnosis of patients with forms of diverticular disease and especially its chronic complications.Summary: the changes of the eyeball identified by experimental and clinical research are typical only for diverticular disease and reflect the severity of its course.