OPTIMIZATION OF CHEMOTHERAPY REGIMENS OF PATIENTS SUFFERING FROM NON-HODGKIN LIMPHOMA
https://doi.org/10.21886/2219-8075-2015-1-50-52
Abstract
Purpose: to evaluate the eff ectiveness of diff erent chemotherapy variants of NHL patients.
Materials and methods: the therapy of 64 B-cell NHL patients aged 21-83 (38 males and 28 females) has been analysed. Th e eff ectiveness of the treatment was evaluated aft er the third cycle of therapy and inductional course of treatment as well as aft er the completion of the entire treatment program.
Results: general eff ectiveness of the treatment made 80% (20 patients), full remission made 52% (15 patients), partial remission made 28% (7 patients), stabilization was achieved in 2 cases (2 patients) (8%), in three cases (3 patients) there was progressiveness of the disease. In the structure of aft er-eff ects the prevailing ones were: hematologic toxicity III-IVst. (56% of the patients), infection (48% of the patients), hemorrhagic syndrome (13% of the patients).
Summary: contemporary PCT’s conducted according to prognostic risk groups, allows to achieve high survival rates for the vast majority of patients with NHL.
About the Authors
Y. A. Kireeva
Rostov State Medical University, Faculty of Internal Medicine № 2, Hematology Department
Russian Federation
Russian Federation
D. I. Harish
Rostov State Medical University, Faculty of Internal Medicine № 2, Hematology Department
Russian Federation
Russian Federation
E. V. Burnasheva
Rostov State Medical University, Faculty of Internal Medicine № 2, Hematology Department
Russian Federation
Russian Federation
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Review
For citations:
Kireeva Y.A., Harish D.I., Burnasheva E.V. OPTIMIZATION OF CHEMOTHERAPY REGIMENS OF PATIENTS SUFFERING FROM NON-HODGKIN LIMPHOMA. Medical Herald of the South of Russia. 2015;(1):50-52. (In Russ.) https://doi.org/10.21886/2219-8075-2015-1-50-52
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