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DYNAMICS OF CHANGES OF THE HEMATOKRIT LEVEL IN NEWBORNS IN CRITICAL CONDITIONS IN RESPONSE TO SELENASE’S INTRODUCTION

https://doi.org/10.21886/2219-8075-2013-4-65-69

Abstract

Purpose: To improve the results of treatment of newborns with respiratory distress syndrome (RDS) and perinatal CNS (central nervous system PP), being in critical conditions, by selenium use.

Materials and Methods: blind, controlled, randomized clinical trial application of selenase in newborn babies with RDS and PP CNS with artificial ventilation (AV) was carries out. 76 newborn children being in a critical condition were surveyed. Randomization was carried out by a computer program of a random number generator. In Group I (n = 36), selenase was entered in doses of 10 mg / kg / day intravenously slowly for 10 days, II group (n = 40) - control group.

Results: during the test it was found and statistically proved that the group of children receiving selenase, there is an increase by 1,01 times (р < 0,05) level of hematocrit.

Summary: level increase of hematocrit, promoted decrease (by 1,1 times) frequencies of development of anemias at children of the I group and by that, reduced the duration of carried-out IVL and hospitalization duration. 

About the Authors

L. F. Dolotova
Rostov-on-Don research institute of obstetrics and pediatrics
Russian Federation
43, Mechnikova Str., Rostov-on-Don, 344012


V. V. Estrin
Rostov-on-Don research institute of obstetrics and pediatrics
Russian Federation
43, Mechnikova Str., Rostov-on-Don, 344012


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Review

For citations:


Dolotova L.F., Estrin V.V. DYNAMICS OF CHANGES OF THE HEMATOKRIT LEVEL IN NEWBORNS IN CRITICAL CONDITIONS IN RESPONSE TO SELENASE’S INTRODUCTION. Medical Herald of the South of Russia. 2013;(4):65-69. (In Russ.) https://doi.org/10.21886/2219-8075-2013-4-65-69

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ISSN 2219-8075 (Print)
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