INFLUENCE OF ARTIFICIAL HUMAN ADAPTATION TO INTERMITTENT NORMOBARIC ANOXIA ON THE OPTIONS OF ERYTHROCYTES OF CIRCULATING BLOOD
https://doi.org/10.21886/2219-8075-2014-4-31-34
Abstract
Purpose: to estimate changes and dynamics of the options of circulating blood erythrocytes in artificial human adaptation to intermittent normobaric hypoxia.
Materials and methods: Sixteen healthy male volunteers aged 20-24 years were underwent to course of artificial adaptation to intermittent normobaric hypoxia (AAINH): 1,5 h daily for 30 days in the gas atmosphere with an oxygen content of 13.5%. Venous blood samples were collected before exposure (day 0), day after exposure, then after 3 and 6 months.
Results: adaptive changes of red blood cells after the course of AAINH were registered in all cases. Moderate reduction of the number of circulating erythrocytes, hematocrit and average erythrocyte volume were noticed. At the same time such parameter as hemoglobin concentration and it’s content in red blood cell was significantly higher than an average one. The long-term follow up demonstrated that the registered trends were continued.
Summary: use of AAINH accompanied with increasing oxygen capacity of circulating blood (due to the synthesis of improved oxygen capasity of red cells), while «determination» to prevent the deterioration of its rheological properties.
Materials and methods: Sixteen healthy male volunteers aged 20-24 years were underwent to course of artificial adaptation to intermittent normobaric hypoxia (AAINH): 1,5 h daily for 30 days in the gas atmosphere with an oxygen content of 13.5%. Venous blood samples were collected before exposure (day 0), day after exposure, then after 3 and 6 months.
Results: adaptive changes of red blood cells after the course of AAINH were registered in all cases. Moderate reduction of the number of circulating erythrocytes, hematocrit and average erythrocyte volume were noticed. At the same time such parameter as hemoglobin concentration and it’s content in red blood cell was significantly higher than an average one. The long-term follow up demonstrated that the registered trends were continued.
Summary: use of AAINH accompanied with increasing oxygen capacity of circulating blood (due to the synthesis of improved oxygen capasity of red cells), while «determination» to prevent the deterioration of its rheological properties.
About the Authors
T. Y. Bykovskaya
Rostov State Medical University
Russian Federation
Department of health and public health organizations with course of information technology in health and medicine
Russian Federation
Department of health and public health organizations with course of information technology in health and medicine
D. V. Shatov
Rostov Bureau of forensic medicine
Russian Federation
Russian Federation
A. O. Ivanov
RD-M of Institute of Shipbuilding and Naval weapons of Military educational research center of the NAVY “Naval Academy”
Russian Federation
Russian Federation
V. F. Belyaev
RD-M of Institute of Shipbuilding and Naval weapons of Military educational research center of the NAVY “Naval Academy”
Russian Federation
Russian Federation
M. V. Mazur
Bryansk Region Hospital № 1
Russian Federation
Russian Federation
References
1. Ушаков И.Б., Основные профилактические проблемы медицины труда / И.Б. Ушаков, М.Н. Хоменко // Медико-экологические проблемы лиц экстремальных профессий. – М., 2008. – С. 19-20.
2. Юдин В.Е. Медико-психологическая реабилитация лиц опасных профессий с учетом патогенетических механизмов снижения их профессиональных качеств / В.Е. Юдин, А.М. Щегольков, В.П. Ярошенко, В.В. Матвиенко, Р.Ш. Симбердеев // Медицина катастроф. – 2013. – № 1 (81). – С. 22 – 26.
3. Гончаров С.Ф. Современная стратегия медицинской реабилитации лиц опасных профессий: проблемы и перспективы / С.Ф. Гончаров, А.Ю. Лапин, В.Н. Преображенский // Медицина катастроф. – 2003. - № 3–4. - С. 56–58.
4. Шатов Д.В. Влияние длительного периодического пребывания в условиях искусственных нормобарических гипоксических газовых сред на операторскую работоспособность / Д.В. Шатов, А.О. Иванов, В.С. Грошилин и др. // Военно-медицинский журнал. – 2014. – Т. 8. – С. 63-65.
5. Шатов Д.В. Восстановление функциональных возможностей организма специалистов опасных профессий путем использования гипоксических газовых сред / Д.В. Шатов, С.М. Грошилин, А.О. Иванов и др. // Медицинский вестник Юга России. – 2014. – № 2. – С. 108-112.
6. Барбашова З.И. Динамика повышения резистентности организма и адаптивных реакций на клеточном уровне в процессе адаптации к гипоксии / З.И. Барбашова // Успехи физиол. наук. – 1970. – Т. 8, № 3. – С. 70-81.
7. Войткевич В.И. Хроническая гипоксия. Приспособительные реакции организма / В.И. Войткевич. – Л.: Наука, 1973. – 191 с.
8. Бободжанов Ю.Р. К вопросу об адаптации кроветворного аппарата к условиям высокогорья Памира / Ю.Р. Бободжанов // Здравоохранение Таджикистана. – 1980. – С. 83-88.
9. Гржибовский А.М. Типы данных, проверка распределения и описательная статистика / А. М. Гржибовский // Экология человека. – 2008. – № 1. – С. 52–58.
10. Ван Лир Э. Гипоксия / Э. Ван Лир, К. Стикней: Пер. с англ. - М.: Медицина, 1967. - 368 с.
Review
For citations:
Bykovskaya T.Y., Shatov D.V., Ivanov A.O., Belyaev V.F., Mazur M.V. INFLUENCE OF ARTIFICIAL HUMAN ADAPTATION TO INTERMITTENT NORMOBARIC ANOXIA ON THE OPTIONS OF ERYTHROCYTES OF CIRCULATING BLOOD. Medical Herald of the South of Russia. 2014;(4):31-34. (In Russ.) https://doi.org/10.21886/2219-8075-2014-4-31-34
Views:
463
Email this article 