WOMEN BLOOD COAGULATIVE SYSTEM INDICES IN PHYSIOLOGICAL PREGNANCY IN DEPENDENCE ON FETUS’ SEX
https://doi.org/10.21886/2219-8075-2013-4-42-45
Abstract
Purpose: To study the features of the blood coagulation system of women at various stages of normal pregnancy, depending on the sex of the fetus.
Material and Methods: Retrospective evaluation of blood coagulation in 259 women with physiological pregnancy in I, II and III trimester with no abnormalities of the blood was conducted. Of these, 116 women had female fetuses (I group), 143 - male fetuses (II group).
Methods: The clinical, clinical laboratory, biochemical. Results: We found that with increasing gestational age the increased activity of coagulative hemostasis was noted in both clinical groups, but the rate of these changes was higher and reached a maximum in II trimester in women with a male fetus, whereas in women with female fetus pace of these changes was less pronounced.
Summary: These results indicate the existence of differences in the «functional behavior» of individual components of the system of hemostasis in various stages of physiological pregnancy. In women with male fetuses we revealed higher coagulation readiness in physiological pregnancy, indicating the tension of coagulation system in this variant of sexual dimorphism.
About the Authors
T. L. Botasheva
Rostov-on-Don research institute of obstetrics and pediatrics
Russian Federation
43, Mechnikova Str., Rostov-on-Don, 344012
Russian Federation
43, Mechnikova Str., Rostov-on-Don, 344012
V. A. Linde
Rostov-on-Don research institute of obstetrics and pediatrics
Russian Federation
43, Mechnikova Str., Rostov-on-Don, 344012
Russian Federation
43, Mechnikova Str., Rostov-on-Don, 344012
Ye. A. Kapustin
Rostov-on-Don research institute of obstetrics and pediatrics
Russian Federation
43, Mechnikova Str., Rostov-on-Don, 344012
Russian Federation
43, Mechnikova Str., Rostov-on-Don, 344012
V. V. Barinova
Rostov-on-Don research institute of obstetrics and pediatrics
Russian Federation
43, Mechnikova Str., Rostov-on-Don, 344012
Russian Federation
43, Mechnikova Str., Rostov-on-Don, 344012
L. V. Kaushanskaya
Rostov-on-Don research institute of obstetrics and pediatrics
Russian Federation
43, Mechnikova Str., Rostov-on-Don, 344012
Russian Federation
43, Mechnikova Str., Rostov-on-Don, 344012
References
1. Боташева, Т.Л. Сравнительный анализ влияния полового диморфизма на адаптационные особенности функциональной системы «мать-плацента-плод». / Т.Л. Боташева, Е.С. Емельяненко, Е.Б. Гудзь, В.В. Баринова, В.С. Гимбут //XXI съезд физиологического общества имени И.П. Павлова.- Москва – Калуга, 2010.- С. 82.
2. Радзинский, В.Е. Актуальные проблемы современного акушерства (по материалам XVΙΙΙ конгресса FIGO. 2006) / В.Е. Радзинский, А.Н. Гордеев // Акуш. и гин. – 2007. – №6. – С. 83–85.
3. Di Renzo, G.C. Does fetal sex affect pregnancy outcome? / G.C. Di Renzo, А. Rosati, R.D. Sarti, L. Cruciani, A.M. Cutuli. // Gend Med. – 2007. – №4(1). – P.19-30.
4. Hesketh, T. Abnormal sex ratios in human populations: causes and consequences //Proc Natl Acad Sci U S A. - 2006.- V.103(36). – P.13271-5.
5. Knippel, A.J. Role of fetal sex in amniotic fluid alphafetoprotein screening //Prenatal Diagnosis. - 2002. - Volume 22, Issue 10. – P. 941–945.
6. Salafia, C.M. Clinical correlations of placental pathology in preterm pre-eclampsia / C.M. Salafia, J.C. Pezzullo, A. Chidini // Placenta. - 1998. - Vol. 19. - №1.- P. 67-72.
7. Серов, В.Н. Неотложные состояния в акушерстве. // В.Н. Серов, Г.Т. Сухих, И.И. Баранов, А.В. Пырегов, В.Л. Тютюнник, Р.Г. Шмаков. - М., 2011.- 775с.
8. Момот, А.П. Патология гемостаза. Принципы и алгоритмы клинико-лабораторной диагностики / А.П. Момот. – СПб., 2006.- 208с.
Review
For citations:
Botasheva T.L., Linde V.A., Kapustin Ye.A., Barinova V.V., Kaushanskaya L.V. WOMEN BLOOD COAGULATIVE SYSTEM INDICES IN PHYSIOLOGICAL PREGNANCY IN DEPENDENCE ON FETUS’ SEX. Medical Herald of the South of Russia. 2013;(4):42-45. (In Russ.) https://doi.org/10.21886/2219-8075-2013-4-42-45
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