Algorithm of Hepatitis B Vaccinal Prevention at Children with Acute Lymphoblastic Leukemia in Dynamics of Program Therapy
Abstract
Purpose: To create the algorithm of hepatitis B vaccinal prevention at children with acute lymphoblastic leukemia.
Materials and Methods: The data of 181 children with acute lymphoblastic leukemia, from which 99 patients received specific hepatitis B prevention with vaccine «Engerix B», have been investigated. The authors have assessed correlations between efficiency of offered vaccinal prevention and leuco/neutropenia degrees at patients in days of vaccinations. The analysis of hepatitis B infect level at stages of vaccination was carried out.
Results: The algorithm of hepatitis B vaccinal prevention at children with acute lymphoblastic leukemia is offered.
About the Authors
N. V. Opaleva
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Haematology Department
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
E. V. Polevichenko
Rostov State Medical University, Department of Children Diseases № 1
Russian Federation
29 Nakhichevansky st., Rostov-on-Don, 344022
Russian Federation
29 Nakhichevansky st., Rostov-on-Don, 344022
K. S. Aslanyan
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Haematology Department
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
V. V. Zotova
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Immunologic Laboratory
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
E. F. Efremova
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Immunologic Laboratory
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
L. D. Oreshkina
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Haematology Department
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
A. H. Haspekyan
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Haematology Department
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
I. V. Yachenko
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Haematology Department
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
E. V. Vasilieva
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Haematology Department
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
L. V. Goncharova
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Haematology Department
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
N. V. Krasnyanskaya
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Haematology Department
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
N. A. Golovanova
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Haematology Department
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
N. V. Mariina
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Clinicodiagnostic Laboratory
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
N. G. Oginskaya
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Clinicodiagnostic Laboratory
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
T. G. Kuruzyan
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Clinicodiagnostic Laboratory
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
G. V. Erkina
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Clinicodiagnostic Laboratory
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
T. N. Kalinina
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Clinicodiagnostic Laboratory
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
A. M. Shaihutdinova
State Health Care Institution «Regional Children’s Hospital»
Russian Federation
Russian Federation
Clinicodiagnostic Laboratory
14 339 Strelkovoy Divisyi st., Rostov-on-Don, 344085
References
1. Качанов Д.Ю., Шаманская Т.В., Абдуллаев Р.Т. и др. Вакцинация детей с онкологическими заболеваниями //Онкогематология. – 2009. - №1. – С. 57-64.
2. Желудкова О.Г., Русанова М.Г., Пастушенко В.В. и др. Специфическая профилактика гепатита В у детей с острым лимфобластным лейкозом //Вопросы гематологии/онкологии и иммунопатологии в педиатрии. – 2003. – Т. 2, №2. – С. 92 – 95.
3. Предеина Н.С. Иммунопрофилактика гепатита В у детей со злокачественными новообразованиями на фоне полихимиотерапии: автореф. дис. … канд. мед. наук – М., 2004. – 24 с.
4. Moryl-Bujakowska A., Czogala M., Czogala W., Balwierz W. The assessment of efficacy of hepatitis B prophylaxis in children with acute lymphoblastic leukemia //Przegl Lek. – 2004. – Vol. 61, Suppl. 2.– P. 85 – 88.
5. Сафина А.И., Зарипов М.М., Гайнуллина Э.А. Анализ анамнестических данных и осложнений при проведении программного лечения детей с ОЛЛ по протоколу BFM //Гематология и трансфузиология. – 1999. – Т. 44, №6. – С. 31.
6. Иванова Л.Ф., Дмитриева Н.В. Частота инфекционных осложнений у детей с острыми лейкозами на фоне программной терапии //Контроль инфекций, сопроводительная терапия и профилактика у иммунокомпрометированных пациентов: cб. тр. Всерос. науч.-практ. конф. – М., 2005. – C. 40.
7. Переводчикова Н.И. (ред.) Руководство по химиотерапии опухолевых заболеваний / Под ред. Переводчиковой. – 2-е изд., доп. – М.: Практ. мед., 2005. – С. 661-693.
Review
For citations:
Opaleva N.V., Polevichenko E.V., Aslanyan K.S., Zotova V.V., Efremova E.F., Oreshkina L.D., Haspekyan A.H., Yachenko I.V., Vasilieva E.V., Goncharova L.V., Krasnyanskaya N.V., Golovanova N.A., Mariina N.V., Oginskaya N.G., Kuruzyan T.G., Erkina G.V., Kalinina T.N., Shaihutdinova A.M. Algorithm of Hepatitis B Vaccinal Prevention at Children with Acute Lymphoblastic Leukemia in Dynamics of Program Therapy. Medical Herald of the South of Russia. 2010;(2):41-45. (In Russ.)
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