The Role of HELICOBACTER PYLORI in Etiology and Pathogenesis of Chronic Gastroduodenal Pathology
Abstract
Helicobacter pylori plays a major role in the development of chronic gastritis, peptic ulcer disease, gastric adenocarcinoma, MALT-lymphoma. The review presents modern data of epidemiology, genetics and microbiology of H.pylori, about the factors of colonization of gastric mucosa and occurrence of H.pylori-associated disorders depending on the intraspecific genetic diversity and factors of pathogenecity of H.pylori, genetic predisposition, local and general protective immune factors, microecology of the gastrointestinal tract of the host.
About the Authors
E. V. Dudnikova
Rostov State Medical University
Russian Federation
Russian Federation
Department of peadiatrics and neonatology
29 Nakhichevansky st., Rostov-on-Don, 344022
M. A. Shestopalova
Rostov State Medical University
Russian Federation
Russian Federation
Department of peadiatrics and neonatology
29 Nakhichevansky st., Rostov-on-Don, 344022
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Review
For citations:
Dudnikova E.V., Shestopalova M.A. The Role of HELICOBACTER PYLORI in Etiology and Pathogenesis of Chronic Gastroduodenal Pathology. Medical Herald of the South of Russia. 2011;(3):4-8. (In Russ.)
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