Free Radical Oxidation and its Part in Hypoxia Adaptation in Epistaxis
Abstract
Purpose: A comparative study of free radical oxidation in the blood of those suffering from single and recurrent epistaxis.
Materials and Methods: In 98 patients malon dialdegid, superoxiddismutase and total peroxidase activity of blood red cells were examined.
Results: Recurrent epistaxis is shown to be followed by a deteriorated content of red blood cells and haemoglobin, which may result in hypoxia. In this group, FRO takes part in hypoxia adaptation: increased superoxide scavenger activity protects red cells from oxidative damage. Physical exercise tests have proved a low reserve of the anti-oxidant system in the blood of recurrent epistaxis patients.
Summary: The state of the patient, suffering from recurrent epistaxis depends on free radical oxidation system reserves.
About the Authors
T. S. Kolmakova
Rostov State Medical University
Russian Federation
Russian Federation
Medical Biology and Genetics Department
29 Nakhichevansky st, Rostov-on-Don, 344002
N. V. Boyko
Rostov State Medical University
Russian Federation
Russian Federation
ENT Department
29 Nakhichevansky st, Rostov-on-Don, 344002
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Review
For citations:
Kolmakova T.S., Boyko N.V. Free Radical Oxidation and its Part in Hypoxia Adaptation in Epistaxis. Medical Herald of the South of Russia. 2012;(2):57-60. (In Russ.)
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