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Evaluation of Drug Thiotriazoline in Patients with Alcoholic Hepatitis

Abstract

Purpose: To evaluate the clinical efficacy and safety Thiotriazoline in patients with acute alcoholic hepatitis.

Materials and Methods: The study included 67 patients with acute alcoholic hepatitis. Randomized patients were divided into two groups - primary and compared. Patients of the group (n = 35) received traditional treatment, in additionto which was connected hepatoprotector Thiotriazoline.

Results: showed improvement of clinical, biochemical and instrumental parameterswhile taking the drug Thiotriazoline.

Summary: The efficacy of treatment as measured by a combined index of overall effectiveness, the drug is comparable to that tiotreazolin with basic therapy, including the traditionally used hepatoprotectors.

About the Authors

A. V. Tkachev
Rostov State Medical University
Russian Federation

Department of propedutics of internal diseases 

29 Nakhichevansky st., Rostov-on-Don, 344022



T. A. Devlikamova
Rostov State Medical University
Russian Federation

Department of propedutics of internal diseases 

29 Nakhichevansky st., Rostov-on-Don, 344022



Z. H. Yandieva
Rostov State Medical University
Russian Federation

Department of propedutics of internal diseases 

29 Nakhichevansky st., Rostov-on-Don, 344022



A. S. Makarenko
Rostov State Medical University
Russian Federation

Department of propedutics of internal diseases 

29 Nakhichevansky st., Rostov-on-Don, 344022



References

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4. Калинин А.В. Вопросы патогенеза, клиники и лечения алкогольной болезни печени. // Клин. перспект. гастроэнтерол. Гепатол. -2001.- №4. - с. 8–14.

5. Мазур И.А., Волошин Н.А., Чекман И.С., Зименковский Б.С., Стец В.Р. Tиотриазолин: фармакологические аспекты и клиническое применение.-Запорожье, 2005.- 146с.

6. Циркунов В.М. Фармакологические эффекты Титориазолина в гепатологической клинике //Рецепт. – 2008. - №1. – С.69-74.


Review

For citations:


Tkachev A.V., Devlikamova T.A., Yandieva Z.H., Makarenko A.S. Evaluation of Drug Thiotriazoline in Patients with Alcoholic Hepatitis. Medical Herald of the South of Russia. 2012;(1):63-69. (In Russ.)

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ISSN 2219-8075 (Print)
ISSN 2618-7876 (Online)