FUNCTIONAL CHARACTERIZATION OF CELLULAR FACTORS OF THE INNATE IMMUNE PROTECTION IN THE DYNAMICS OF HIV-INFECTION
https://doi.org/10.21886/2219-8075-2013-3-52-55
Abstract
Purpose: To study the pathogenetic significance of cellular factors in the development of innate immunity mediated by HIV infection
Materials and Methods: Oxygen-dependent metabolism of neutrophil granulocytes, the cytolytic activity of NK cells, production of IFN – γ were studied. We observed 36 HIV-infected patients.
Results and Summary: It is shown that after the stage of activation of cellular innate antiviral defense mechanisms formed functional suppression, making a significant contribution to the progression of HIV infection.
About the Authors
L. A. Kotieva
Rostov State Medical University
Russian Federation
Russian Federation
Department of Immunopathology and Allergology of Professional and Training Development Department
29 Nakhichevansky st., Rostov-on-Don, 344022I. I. Andreevа
Rostov State Medical University
Russian Federation
Russian Federation
Department of Immunopathology and Allergology of Professional and Training Development Department
29 Nakhichevansky st., Rostov-on-Don, 344022L. P. Sizyakina
Rostov State Medical University
Russian Federation
Russian Federation
Department of Immunopathology and Allergology of Professional and Training Development Department
29 Nakhichevansky st., Rostov-on-Don, 344022References
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For citations:
Kotieva L.A., Andreevа I.I., Sizyakina L.P. FUNCTIONAL CHARACTERIZATION OF CELLULAR FACTORS OF THE INNATE IMMUNE PROTECTION IN THE DYNAMICS OF HIV-INFECTION. Medical Herald of the South of Russia. 2013;(3):52-55. (In Russ.) https://doi.org/10.21886/2219-8075-2013-3-52-55
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