Role Adaptole in Correction Neurasthenia at Patients with the Syndrome of Angry Intestines (IBS)
Abstract
Purpose: Estimation of clinical efficiency adaptole а in correction of an asthenic syndrome at patients with a syndrome of angry intestines (IBS).
Materials and Methods: 52 patients (38 women and 14 men) with a syndrome of angry intestines (IBS) with presence of various psychopathological frustration of the neurotic register have been included in research. The age of patients varied from 28 till 40 years. Patients received a preparation adaptole in a dose 0, 5 г 2 times a day irrespective of food intake. Course of treatment 1 month. Appointment of accompanying psychotropic preparations was not supposed. The diagnosis is verified by modern clinic-tool methods of research. The psychometric research was conducted.
Results: The analysis of biographical particulars has shown, that patients had expressed disturbing frustration. In group of patients with constipation variant IBS high level personal was observed and an average level of situational, that correlates with results of uneasiness on scale Sheehan, the test of color elections Lusher. Clinically authentic infringements of nervous vegetative system are found out in patients with IBS. By the end of a 3-week course of application adaptole а practically has completely disappeared somatization alarm displays, painful sensations and clinical symptoms somatovegetative were stopped to dysfunction, dissomnitice frustration, antivitale experiences. In the course of carrying out of clinical research insignificant by-effects of therapy have been found out.
Summary: Аdoptole renders moderated tranquilizing influence and practically does not cause by-effects. The preparation can have metabolic an effect, normalising the various metabolic processes broken by stress, besides, аdoptole can influence functioning neurosensitive systems.
About the Authors
E. E. AlekseevRussian Federation
Department of Propedutics of Internal Diseases
29 Nakhichevansky st., Rostov-on-Don, 344022
E. N. Veselova
Russian Federation
Department of Propedutics of Internal Diseases
29 Nakhichevansky st., Rostov-on-Don, 344022
References
1. Табачников С.І., Волошин П.В. До всесвітнього дня здоров’я, присвяченого охороні психічного здоров’я //Архів психіатрії. — 2001. — № 1–2. — С. 5–6.
2. Михайлов Б. В., Козидубова В. М., Марута Н. А. и др. Актуальные проблемы социальной психиатрии, психотерапии и медицинской психологии в Украине // Вісник психічного здоров’я. — 2009. — № 1. —С. 16–18.
3. Чутко Л.С., Сурушкина С.Ю., Рожкова А.В. Современные подходы к диагностике и лечению неврастении. Учебно-методическое пособие. Санкт-Петербург, 2011. - С.3-10
4. Volz H.P. Controlled clinical trials of hypericum extracts in depressed patients—an overview //Pharmacopsychiat. - 1997. - 30(suppl). - P.72–76.
5. Spielberger C.D., Gorsuch R.L., Lushene R.E. Psychometric research was carried out Hanina J.L.’s Russified version., 1970.
6. Sheehan D.V., Sheehan K. Estimated clinical scale of alarm. - 1983.
7. Точилов В. А. Опыт лечения депрессии адаптолом // Журнал неврологии и психиатрии им. С. С. Корсакова. — 2000. — Т. 100, № 5. — С. 63.
8. Linde K., Ramirez G. et al. St. John works for depression — an overview and meta-analysis of randomized clinical trials //British Medical Journal. — 2006. — Vol. 316. — P. 252–258.
Review
For citations:
Alekseev E.E., Veselova E.N. Role Adaptole in Correction Neurasthenia at Patients with the Syndrome of Angry Intestines (IBS). Medical Herald of the South of Russia. 2012;(1):26-28. (In Russ.)