THE PECULIARITIES OF ACCUMULATION OF COLLAGENS I AND III TYPES AND ELASTIN IN THE LIGAMENTS OF THE UTERUS WHEN THE PROLAPSE GENIALI (IMMUNOHISTOCHEMISTRY)
https://doi.org/10.21886/2219-8075-2014-4-95-100
Abstract
Purpose: to study the molecular and biochemical changes underlying the PG and immunohistochemical characteristics of accumulation of collagens I and III and elastin in the sacro-uterine and round ligaments of the uterus at PG.
Materials and methods: the examined 15 patients aged from 42 to 65 years with full and partial prolapse of the uterus and vaginal walls, which have had a hysterectomy vaginal access. The control group consisted of 15 women ranging in age from 35 to 52 years with no signs of GHGs, which have had a hysterectomy abdominal access for uterine fibroids, adenomyosis, endometrial pathology. All patients were comparable in parieto birth. In the groups evaluated the results of morphological and immunohistochemical research biopsies of the sacro-uterine and round ligaments.
Materials and methods: the examined 15 patients aged from 42 to 65 years with full and partial prolapse of the uterus and vaginal walls, which have had a hysterectomy vaginal access. The control group consisted of 15 women ranging in age from 35 to 52 years with no signs of GHGs, which have had a hysterectomy abdominal access for uterine fibroids, adenomyosis, endometrial pathology. All patients were comparable in parieto birth. In the groups evaluated the results of morphological and immunohistochemical research biopsies of the sacro-uterine and round ligaments.
About the Authors
V. E. Radzinskiy
Russian peoples friendship University
Russian Federation
Department of obstetrics, gynecology and reproductive medicine FPC MR
Russian Federation
Department of obstetrics, gynecology and reproductive medicine FPC MR
M. L. Khanzadyan
Russian peoples friendship University
Russian Federation
Department of obstetrics, gynecology and reproductive medicine FPC MR
Russian Federation
Department of obstetrics, gynecology and reproductive medicine FPC MR
T. A. Demura
GBOU VPO First MGMU them. I. M. Sechenov Moscow medical Academy
Russian Federation
Department of pathological anatomy to them. academician A. I. Strukova, Moscow
Russian Federation
Department of pathological anatomy to them. academician A. I. Strukova, Moscow
R. Cоnnon
Russian peoples friendship University
Russian Federation
Department of obstetrics, gynecology and reproductive medicine FPC MR
Russian Federation
Department of obstetrics, gynecology and reproductive medicine FPC MR
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For citations:
Radzinskiy V.E., Khanzadyan M.L., Demura T.A., Cоnnon R. THE PECULIARITIES OF ACCUMULATION OF COLLAGENS I AND III TYPES AND ELASTIN IN THE LIGAMENTS OF THE UTERUS WHEN THE PROLAPSE GENIALI (IMMUNOHISTOCHEMISTRY). Medical Herald of the South of Russia. 2014;(4):95-100. (In Russ.) https://doi.org/10.21886/2219-8075-2014-4-95-100
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