ВЛИЯНИЕ КИСЛОРОДНОГО СТАТУСА НА ПОКАЗАТЕЛИ ОКСИДАТИВНОГО СТРЕССА У НОВОРОЖДЕННЫХ С ДЫХАТЕЛЬНЫМИ РАССТРОЙСТВАМИ, НАХОДЯЩИХСЯ НА ИСКУССТВЕННОЙ ВЕНТИЛЯЦИИ ЛЕГКИХ
https://doi.org/10.21886/2219-8075-2015-3-100-103
Abstract
Purpose: to analyze the effectiveness of cerebral oximetry to optimize the oxygen concentration (FiO2) in the inspired mixture in the application of artificial ventilation (AV) and the influence of oxygen status on indicators of oxidative stress in newborns.
Materials and Methods: total of 75 neonates receiving mechanical ventilation. Patients of the main group (n = 38) modes of mechanical ventilation and FiO2 were determined under the control of cerebral oximetry. In the control group modes of mechanical ventilation and FiO2 were set according to the partial oxygen pressure in the capillary blood. All patients were determined peroxide oxidation products and protein in serum.
Results: f reduction in the duration of mechanical ventilation, the concentration FiO2, levels of markers of oxidative stress in patients in the study group.
Summary: cerebral oximetry during mechanical ventilation to optimize the oxygen status, reduce the risk of oxidative stress in newborns in critical conditions.
About the Author
A. V. Simonova
Research Institute of Obstetrics and Pediatrics, Department of Anesthesiology and Intensive Care
Russian Federation
Russian Federation
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Review
For citations:
Simonova A.V. . Medical Herald of the South of Russia. 2015;(3):100-103. (In Russ.) https://doi.org/10.21886/2219-8075-2015-3-100-103
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