Magnetic resonance morphometry in the assessment of gender dimorphism of the structural organization of the brain in schoolchildren 15–16 years old
E. A. Finota,
N. V. Zarytovskaya,
A. S. Kalmykova,
V. S. Kashnikov,
A. I. Firumyants,
I. N. Bulakhova https://doi.org/10.21886/2219-8075-2026-17-1-57-62
Abstract
Objective: to identify the morphometric characteristics and sex differences of the white and gray matter of the brain in school-age children. Materials and methods: the results of MR tomograms of the brain of 123 healthy schoolchildren aged 15-16 with normal physical development, who were examined before participating in sports competitions, were analyzed. The FreeSurfer software was used. Results: automatic segmentation, reconstruction and quantitative analysis of brain structures were performed, correction of the total intracranial volume was performed. Without adjusting for intracranial volume, the indicators of the white gray matter of the brain in boys were statistically significantly higher than those of girls. Conclusions: the predominance of the relative volumes of the cortical structures of the brain in girls over the indicators of their male peers was noted.
About the Authors
E. A. Finota
Stavropol State Medical University
Russian Federation
Competing Interests:
Russian Federation
Elena A Finota, Assistant Professor, Department of Propaedeutics of Childhood Diseases
Stavropol
Competing Interests:
Authors declares no conflict of interest.
N. V. Zarytovskaya
Stavropol State Medical University
Russian Federation
Competing Interests:
Russian Federation
Natalia V Zarytovskaya, Dr. Sci. (Med.), Professor Department of Propaedeutics of Childhood Diseases
Stavropol
Competing Interests:
Authors declares no conflict of interest.
A. S. Kalmykova
Stavropol State Medical University
Russian Federation
Competing Interests:
Russian Federation
Angelina S Kalmykova, Dr. Sci. (Med.), Professor
Stavropol
Competing Interests:
Authors declares no conflict of interest.
V. S. Kashnikov
Stavropol State Medical University
Russian Federation
Competing Interests:
Russian Federation
Vyacheslav S Kashnikov, Dr. Sci. (Med.), Professor of the Department of Normal and Pathological Physiology
Stavropol
Competing Interests:
Authors declares no conflict of interest.
A. I. Firumyants
Research Institute of Pediatrics and Children's Health, Scientific and Clinical Center No. 2, Federal State Budgetary Scientific Institution "Russian Scientific Center of Surgery n. a. Academician B.V. Petrovsky" of the Ministry of Education and Science of the Russian Federation
Russian Federation
Competing Interests:
Russian Federation
Alexey I. Firumyants, Radiologist, Junior Researcher at the Department of Innovative Diagnostic Research Methods
Stavropol
Competing Interests:
Authors declares no conflict of interest.
I. N. Bulakhova
Stavropolsky Regional Clinical Consulting and Diagnostic Center
Russian Federation
Competing Interests:
Russian Federation
Irina N Bulakhova, Radiologist
Stavropol
Competing Interests:
Authors declares no conflict of interest.
References
1. Piradov M.A., Tanashyan M.M., Krotenkova M.V., Bryukhov V.V., Kremneva E.I., Konovalov R.N. State-of-the-art neuroimaging techniques. Annals of clinical and experimental neurology. 2015;9(4):11-18. (In Russ.) eLIBRARY ID: 25435173 EDN: VKPNYV
2. Bakhareva N.S., Avakimyan S.B., Baraeva L.M., Gashumova R.A., Khromov D.A., et al. Gender differences in morphometric parameters of cerebral hemispheres in twelveyear-old children. International Research Journal. 2024;9(147). (In Russ.) https://doi.org/10.60797/IRJ.2024.147.48
3. Karkashadze G.A., Firumyants A.I., Shilko N.S., Sergienko N.S., Nesterova Yu.V., et al. Structural morphometry of the brain in children with attention deficit hyperactivity disorder and comorbid mild cognitive impairment. Voprosy sovremennoi pediatrii — Current Pediatrics. 2024;23(6):466–482. (In Russ). https://doi.org/10.15690/vsp.v23i6.2838
4. Backhausen LL, Herting MM, Tamnes CK, Vetter NC. Best Practices in Structural Neuroimaging of Neurodevelopmental Disorders. Neuropsychol Rev. 2022;32(2):400-418. https://doi.org/10.1007/s11065-021-09496-2
5. Firumyants A.I., Namazova-Baranova L.S., Karkashadze G.A., Kovtun O.P., Dyachenko V.V., det al. Brain Morphometry is an Advanced Method of Neuroimaging Mapping in Children. Current Pediatrics. 2023;22(6):521-527. (In Russ.) https://doi.org/10.15690/vsp.v22i6.2707
6. Baibakov S.Y., Bakhareva N.S., Fedko V.A., Baraeva L.M., Blikyan A.V., et al. Gender differences in encephalometric parameters of the cerebral hemispheres in nine-year-old children. International Research Journal. 2022;11(125). (In Russ.) https://doi.org/10.23670/IRJ.2022.125.94
7. Giedd JN, Raznahan A, Mills KL, Lenroot RK. Review: magnetic resonance imaging of male/female differences in human adolescent brain anatomy. Biol Sex Differ. 2012;3(1):19. https://doi.org/10.1186/2042-6410-3-19
8. Baibakov S.E., Bakhareva N.S., Yusupov T.R., Gordeeva E.K., Salomatina E.A., et al. Gender differences in the size of pons varolii and medulla oblongata in children during second childhood. Mezhdunarodnyi nauchno-issledovatel'skii zhurnal. 2022;7(2):121. (In Russ.) https://doi.org/10.23670/IRJ.2022.121.7.044
9. Polunina A.G., Bryun E.A. Neuroanatomic differences of the brain in males and females. Annals of clinical and experimental neurology. 2017;11(3):68-75. (In Russ.) eLIBRARY ID: 30069983 EDN: ZIAOGB
10. Vijayakumar N, Mills KL, Alexander-Bloch A, Tamnes CK, Whittle S. Structural brain development: A review of methodological approaches and best practices. Dev Cogn Neurosci. 2018;33:129-148. https://doi.org/10.1016/j.dcn.2017.11.008
11. Bogolepova IN, Krotenkova MV, Konovalov RN, Agapov PA, Malofeeva IG, Bikmeev AT. Gender morphology of Broca’s motor speech area. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(9):96-100. (In Russ.) https://doi.org/10.17116/jnevro202312309196
12. Yerokhin M.V., Taschilkin A.I., Pozdnyakov A.V., Orel V.I., Lvov V.S. Possibilities of VBM of the brain in children with hypoxic-ischemic encephalopathy. Vizualizatsiya v meditsine. 2020;2(1):32-39. (In Russ.) eLIBRARY ID: 43596512 EDN: WDLXF
13. Krasniak EV, Bondarev KV. Past, present and future of gender medicine in Russia and worldwide. Russian Journal of Preventive Medicine. 2022;25(10):84-90. (In Russ.) https://doi.org/10.17116/profmed20222510184
14. Turchinskaya I.A., Shtentsel R.E., Trufanov A.G. Magnetic resonance imaging in the diagnosis of functional brain changes in teenage girls with normal menstrual cycle. International Research Journal. 2024;3(141). (In Russ.) https://doi.org/10.23670/IRJ.2024.141.57
15.
Review
For citations:
Finota E.A., Zarytovskaya N.V., Kalmykova A.S., Kashnikov V.S., Firumyants A.I., Bulakhova I.N. Magnetic resonance morphometry in the assessment of gender dimorphism of the structural organization of the brain in schoolchildren 15–16 years old. Medical Herald of the South of Russia. 2026;17(1):57-62. (In Russ.) https://doi.org/10.21886/2219-8075-2026-17-1-57-62
Views:
224
JATS XML
Email this article 