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Clinical case of infectious endocarditis fatal outcome in a patient with opiate addiction

https://doi.org/10.21886/2219-8075-2025-16-4-41-46

Abstract

Infectious endocarditis (IE) of injecting drug users (IDU) remains an unresolved and very significant medical and social problem due to the rapid increase in the number of drug-addicted patients, high frequency of complications and hospital mortality, which determines the relevance of the search for their predictors, requires optimization of treatment in order to improve the prognosis in this category of patients. The article demonstrates our own clinical observation of a young IDU patient with primary IE and the formation of a combined aortic defect, Valsalva sinus abscess and its rupture into the right ventricular cavity with the development of acute cardiac activity decompensation, multiple organ failure, ventricular fibrillation, which led to the death of the patient. In view of the extremely serious condition of the patient, it was not possible to timely transport him to a cardiac surgery center for surgical treatment. The most probable causes of complications and death, as well as the possibilities of their prevention, are discussed.

About the Authors

E. S. Vavilina
Kursk State Medical University
Russian Federation

Elena S. Vavilina, Cand. Sci. (Med.), Associate Professor of the Department of Internal Diseases N 1

Kursk


Competing Interests:

Authors declares no conflict of interest



N. S. Meshcherina
Kursk State Medical University
Russian Federation

Natalia S. Meshcherina, Dr. Sci. (Med.), Associate Professor, The Head of the Department оf Internal Diseases №1, Vice-Rector for Medical Activities and Development of Regional Healthcare

Kursk


Competing Interests:

Authors declares no conflict of interest



O. G. Schatalova
Kursk State Medical University
Russian Federation

Olga G. Schatalova, 6-year student of pediatric faculty

Kursk


Competing Interests:

Authors declares no conflict of interest



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Review

For citations:


Vavilina E.S., Meshcherina N.S., Schatalova O.G. Clinical case of infectious endocarditis fatal outcome in a patient with opiate addiction. Medical Herald of the South of Russia. 2025;16(4):41-46. (In Russ.) https://doi.org/10.21886/2219-8075-2025-16-4-41-46

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ISSN 2219-8075 (Print)
ISSN 2618-7876 (Online)