Modern approaches to studying non-specific prevention of cholera
https://doi.org/10.21886/2219-8075-2025-16-4-74-83
Abstract
Cholera remains a serious public health problem, especially in low-income countries with a lack of water supply and sanitation education among the population. Vaccination is currently the main measure to prevent this infection in endemic areas and during outbreaks, but for a number of reasons its effectiveness may decrease: there is always a group of people who have contraindications to vaccination and do not respond to the vaccine. In addition, there are problems with the delivery, storage and transportation of vaccine preparations. All these factors necessitate the search, development and implementation of various new means to prevent the spread of the disease. The purpose of this review was to analyze the literature data on the study of the possibility of using antibiotics, bacteriophages, probiotic microorganisms, plant components and other substances for the prevention of cholera. The list of references includes 56 sources for the last ten years, taken from databases: RSCI, eLibrary, MedLine, PubMed.
Supporting agencies: The study did not have sponsorship.
About the Authors
A. V. Filippenko
Rostov-on-Don Anti-Plague Institute of Rospotrebnadzor
Russian Federation
Competing Interests:
Russian Federation
Anna V. Filippenko, Cand. Sci. (Biology), Research Laboratory of Immunology
Rostov-on-Don
Competing Interests:
Authors declares no conflict of interest
I. A. Ivanova
Rostov-on-Don Anti-Plague Institute of Rospotrebnadzor
Russian Federation
Competing Interests:
Russian Federation
Inna A. Ivanova, Cand. Sci. (Biology), Leading Researcher with Acting Head of the Laboratory Immunology
Rostov-on-Don
Competing Interests:
Authors declares no conflict of interest
N. D. Omelchenko
Rostov-on-Don Anti-Plague Institute of Rospotrebnadzor
Russian Federation
Competing Interests:
Russian Federation
Natalia D. Omelchenko, Cand. Sci. (Med.), Senior Researcher Laboratory of Immunology
Rostov-on-Don
Competing Interests:
Authors declares no conflict of interest
A. A. Trufanova
Rostov-on-Don Anti-Plague Institute of Rospotrebnadzor
Russian Federation
Competing Interests:
Russian Federation
Anastasia A. Trufanova, Junior Researcher, Laboratory of Immunology
Rostov-on-Don
Competing Interests:
Authors declares no conflict of interest
O. G. Zhukova
Rostov-on-Don Anti-Plague Institute of Rospotrebnadzor
Russian Federation
Competing Interests:
Russian Federation
Olga G. Zhukova, Junior Researcher at the Laboratory of Immunology
Rostov-on-Don
Competing Interests:
Authors declares no conflict of interest
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For citations:
Filippenko A.V., Ivanova I.A., Omelchenko N.D., Trufanova A.A., Zhukova O.G. Modern approaches to studying non-specific prevention of cholera. Medical Herald of the South of Russia. 2025;16(4):74-83. (In Russ.) https://doi.org/10.21886/2219-8075-2025-16-4-74-83
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