Современные направления изучения средств неспецифической профилактики холеры

Холера остается серьезной проблемой общественного здравоохранения, особенно в странах с низким уровнем доходов, отсутствием водоснабжения и санитарно-просветительного образования среди населения. Вакцинация на сегодняшний день является основной мерой профилактики этой инфекции в эндемичных районах и во время вспышек, однако по ряду причин её эффективность может снижаться: всегда есть группа лиц, имеющих противопоказания к проведению вакцинации и не отвечающих на вакцину. Кроме того, существуют проблемы с доставкой, хранением и транспортировкой вакцинных препаратов. Все эти факторы обусловливают необходимость поиска, разработки и внедрения различных новых средств, препятствующих распространению заболевания. Целью данного обзора являлся анализ литературных данных, посвящённых изучению возможности использования антибиотиков, бактериофагов, пробиотических микроорганизмов, растительных компонентов и других веществ, для профилактики холеры. Список литературы включает 56 источников за последние десять лет, взятых из баз данных «РИНЦ», «eLibrary», «MedLine», «PubMed».

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