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A case of indirect hyperbilirubinemia in a child with diabetic fetopathy

https://doi.org/10.21886/2219-8075-2025-16-2-92-100

Abstract

A clinical case of indirect hyperbilirubinemia in a child with diabetic fetopathy is presented. Diagnosis and comprehensive treatment treatment of children with this pathology is difficult due to the variety of causes that cause the development of indirect or direct hyperbilirubinemia or a combination of them. Jaundice in young children is a frequent clinical symptom in practical medicine, and in severe cases may be accompanied by a manifestation of neurotoxicity of indirect bilirubin, accompanied by some delay in diagnosis, cases of prolonged course, or be a harbinger of a serious underlying disease, leading to fatal outcomes. Therefore, a symptom of jaundice should not be perceived as a routine condition. Regardless of the level of hyperbilirubinemia, the appearance of jaundice in the first 24 hours of life, the high rate of hourly increase in serum bilirubin levels, combined with the severity of hemolysis, require urgent examination and treatment of in young children. The main importance for the diagnosis and prognosis of the disease in children with hyperbilirubinemia is the rapid increase in jaundice with visible staining of the palms and feet. This requires an urgent determination of the concentration of bilirubin in the blood serum. It should be noted that in most cases, non-invasive, transcutaneous determination of bilirubin levels by a bilirubinometer does not replace standard laboratory testing, but allows you to avoid unjustified collection of capillary or venous blood in newborns and not miss dangerous hyperbilirubinemia, especially with early discharge from the hospital.

About the Authors

A. A. Lebedenko
Rostov State Medical University
Russian Federation

Alexander A. Lebedenko, Dr. Sci. (Med.), Director of the Newborns and Unborn Children of the National Research Institute , Head of the Department of Pediatric Diseases No. 2 

Rostov-on-don 


Competing Interests:

 Authors declare no conflict of interest 



T. B. Kozyreva
Rostov State Medical University
Russian Federation

Tatyana B. Kozyreva, Cand. Sci. (Med.), Associate Professor of the Department of Children's Diseases No. 2

Rostov-on-don  


Competing Interests:

 Authors declare no conflict of interest 



K. I. Lazareva
Rostov State Medical University
Russian Federation

Karina I. Lazareva, Head of the Department of Pathology of Newborns and Unborn Children of the National Research Institute 

Rostov-on-don 


Competing Interests:

 Authors declare no conflict of interest 



E. F. Alieva
Rostov State Medical University
Russian Federation

Elvira F. Alieva, doctor of the Department of Pathology of Newborns and Unborn, Children of the National Research Institute 

Rostov-on-don 


Competing Interests:

 Authors declare no conflict of interest 



A. I. Chekhova
Rostov State Medical University
Russian Federation

Anastasia I. Chekhovа, 6th year student of the Pediatric Faculty 

Rostov-on-don 


Competing Interests:

 Authors declare no conflict of interest 



References

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Review

For citations:


Lebedenko A.A., Kozyreva T.B., Lazareva K.I., Alieva E.F., Chekhova A.I. A case of indirect hyperbilirubinemia in a child with diabetic fetopathy. Medical Herald of the South of Russia. 2025;16(2):92-100. (In Russ.) https://doi.org/10.21886/2219-8075-2025-16-2-92-100

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ISSN 2219-8075 (Print)
ISSN 2618-7876 (Online)