Level Cytokines in Whey of Blood at Children of the First Months of Life with Herpesvirus Infection of the Central Nervous System
Abstract
Purpose: To study features of neurologic semiology both a level of interleukin-2 (IL-2) and interleukin-4 (IL-4) at children of the first months of life with defeat of nervous system at herpes virus infection.
Material and Methods: Сlinical and laboratory examination of the 221 newborns with defeat of nervous system at herpesvirus infection (cytomegalovirus, herpes simplex virus infections, Epstein-Barr virus infections) were done. Follow-up immunological studies were undertaken to examine the levels interleukin 2 (IL -2) and interleukin - 4 (IL -4) in the sera at children of the first months of a life with herpes virus infection. Control group consisted of 12 healthy newborns.
Results: All children with herpes virus infection had neurologic semiology of various degrees. Dependence of levels IL-2 and IL-4 from a virus kind is revealed.
Summary: The significant increase in the levels of IL -2 was found at children with serious form cytomegalovirus infection.
About the Authors
L. V. Kravchenko
Rostov Scientific Research Institute of Obstetrics and Pediatrics
Russian Federation
43 Mechnicova St., Rostov-on-don, 344012
Russian Federation
43 Mechnicova St., Rostov-on-don, 344012
A. A. Afonin
Rostov Scientific Research Institute of Obstetrics and Pediatrics
Russian Federation
43 Mechnicova St., Rostov-on-don, 344012
Russian Federation
43 Mechnicova St., Rostov-on-don, 344012
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Review
For citations:
Kravchenko L.V., Afonin A.A. Level Cytokines in Whey of Blood at Children of the First Months of Life with Herpesvirus Infection of the Central Nervous System. Medical Herald of the South of Russia. 2012;(4):18-22. (In Russ.)
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