A new method of etiopathogenetic treatment of patients with influenza
Yu. M. Ambalov,
D. V. Sizyakin, 
D. V. Dontsov,
A. A. Kurdin,
A. P. Kovalenko,
M. A. Proydakov,
N. I. Mamedova,
D. S. Ryazanova
D. V. Dontsov,
A. A. Kurdin,
A. P. Kovalenko,
M. A. Proydakov,
N. I. Mamedova,
D. S. Ryazanova https://doi.org/10.21886/2219-8075-2020-11-3-34-39
Abstract
Purpose: to develop an effective and safe method for the etiopathogenetic treatment of influenza patients, aimed at increasing the effectiveness of the existing standard treatment using the antiviral drug oseltamivir.
Materials and methods: 150 patients with a verified diagnosis of influenza were taken under observation. All of the participants were divided by randomization into two groups (n1 = 77, n2 = 73) which had the same initial clinical and laboratory characteristics. I group’s patients received standard antiviral therapy using oseltamivir. Patients of the II group at the same time as oseltamivir additionally received an aqueous solution of rehydron for 5 days. All patients underwent determination of the acidity of the mucous membrane of the oropharynx immediately before the start of antiviral therapy and immediately after its completion.
Results: patients additionally receiving rehydron had a more rapid leveling of the main symptoms of influenza and a decrease in the frequency of its complications compared with people who received only standard treatment.
Conclusions: the developed method of etiopathogenetic treatment of patients with influenza is characterized by a proven level of effectiveness, which is associated with the corrective effect of rehydron on the acid-base balance of the mucous membranes of the respiratory tract. The data obtained in the course of the study indicate not only the absolute scientific novelty of the developed method, but also its applied significance for practical public health.
About the Authors
Yu. M. Ambalov
Rostov State Medical University
Russian Federation
Russian Federation
Yury М. Ambalov, Dr. Sci. (Med.), professor, Head of the department of infectious diseases
Rostov-on-Don
D. V. Sizyakin
City Hospital № 1 named after N.А. Semashko, Rostov-on-Don
Russian Federation
Russian Federation
Dmitry V. Sizyakin, Honored Doctor of the Russian Federation, Dr. Sci. (Med.), professor, chief physician
Rostov-on-Don
D. V. Dontsov
Rostov State Medical University
Russian Federation
Russian Federation
Denis V. Dontsov, Dr. Sci. (Med.), associate professor, professor of the Department of Infectious Diseases
Rostov-on-Don
A. A. Kurdin
Rostov State Medical University
Russian Federation
Russian Federation
Alexey A. Kurdin, postgraduate student, Department of Infectious Diseases
Rostov-on-Don
A. P. Kovalenko
Rostov State Medical University
Russian Federation
Russian Federation
Anna P. Kovalenko, Cand. Sci. (Med.), associate professor, associate professor of the department of infectious diseases
Rostov-on-Don
M. A. Proydakov
Rostov State Medical University
Mikhail A. Proydakov, Cand. Sci. (Med.), associate professor, associate professor of the department of infectious diseases
Rostov-on-Don
N. I. Mamedova
Rostov State Medical University
Russian Federation
Russian Federation
Nonna I. Mamedova, Cand. Sci. (Med.), associate professor, associate professor of the department of infectious diseases
Rostov-on-Don
D. S. Ryazanova
Rostov State Medical University
Daria S. Ryazanova, head of the student group at the Department of Infectious Diseases
Rostov-on-Don
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Review
For citations:
Ambalov Yu.M., Sizyakin D.V., Dontsov D.V., Kurdin A.A., Kovalenko A.P., Proydakov M.A., Mamedova N.I., Ryazanova D.S. A new method of etiopathogenetic treatment of patients with influenza. Medical Herald of the South of Russia. 2020;11(3):34-39. (In Russ.) https://doi.org/10.21886/2219-8075-2020-11-3-34-39
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