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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">mvjr</journal-id><journal-title-group><journal-title xml:lang="en">Medical Herald of the South of Russia</journal-title><trans-title-group xml:lang="ru"><trans-title>Медицинский вестник Юга России</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2219-8075</issn><issn pub-type="epub">2618-7876</issn><publisher><publisher-name>The Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2219-8075-2022-13-4-22-27</article-id><article-id custom-type="elpub" pub-id-type="custom">mvjr-1706</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OCCUPATIONAL MEDICINE</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>3.2.4 МЕДИЦИНА ТРУДА</subject></subj-group></article-categories><title-group><article-title>Analysis of the health status of medical workers based on the results of mandatory periodic examinations</article-title><trans-title-group xml:lang="ru"><trans-title>Анализ состояния здоровья медицинских работников по результатам проведения обязательных периодических медицинских осмотров</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7530-6416</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovko</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Головко Елена Анатольевна – кандидат медицинских наук, начальник.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Elena A. Golovko - Cand. Sci. (Med.), нead of State Novosibirsk Regional Clinical Hospital of War Veterans.</p><p>Novosibirsk</p></bio><email xlink:type="simple">gnokgvv@nso.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9937-945X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Несина</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nessina</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Несина Ирина Алексеевна - доктор медицинских наук, профессор, профессор кафедры неотложной терапии с эндокринологией и профпатологией, НГМУ; ведущий научный сотрудник отдела гигиенических исследований, Новосибирский НИИ гигиены.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Irina N. Nesina - Dr. Sci. (Med.), Professor of the Department of Emergency Therapy with Endocrinology and Occupational Pathology, Novosibirsk State Medical University, Leading Researcher of the Department of Hygienic Research of the Novosibirsk Research Institute of Hygiene.</p><p>Novosibirsk</p></bio><email xlink:type="simple">nesinairina@ngs.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8283-2342</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнова</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Smirnova</surname><given-names>E. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Смирнова Елена Леонидовна - доктор медицинских наук, доцент, профессор кафедры неотложной терапии с эндокринологией и профпатологией, НГМУ; профессор отдела образования, НИИ терапии и профилактической медицины – филиал ФИЦ ИЦиГ СО РАН.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Elena L. Smirnova - Dr. Sci. (Med.), Associate Professor, Professor of the Department of Emergency Therapy with Endocrinology and Occupational Pathology, Novosibirsk State Medical University, Professor of the Department of Education of the Research Institute of Pathology and Preventive Medicine - Branch of the Federal Research Center Institute of Cytology and Genetics SB RAS".</p><p>Novosibirsk</p></bio><email xlink:type="simple">smelel@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1422-4211</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Потеряева</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Poteruaeva</surname><given-names>E. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Потеряева Елена Леонидовна – доктор медицинских наук, профессор, заведующая кафедрой неотложной терапии с эндокринологией и профпатологией, НГМУ; главный научный сотрудник отдела гигиенических исследований, Новосибирский НИИ гигиены.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Elena L. Poteryaeva - Dr. Sci. (Med.), Professor, Head of the Department of Emergency Therapy with Endocrinology and Occupational Pathology, Novosibirsk State Medical University, Chief Researcher of the Department of Hygiene Research, Novosibirsk Re-search Institute of Hygiene.</p><p>Novosibirsk</p></bio><email xlink:type="simple">sovetmedin@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фигуренко</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Figurenko</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фигуренеко Наталья Николаевна - заместитель начальника.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Natalia N. Figureneko - Deputy Head of the State Medical Institution of the State Regional Clinical Hospital of War Veterans.</p><p>Novosibirsk</p></bio><email xlink:type="simple">gnokgvv@nso.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5942-6490</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демешко</surname><given-names>К. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Demeshko</surname><given-names>K. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Демешко Ксения Олеговна - начальник службы сопровождения пациентов.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Ksenia O. Demeshko - Head of the Patient Support Service of the State Regional Clinical Hospital of War Veterans.</p><p>Novosibirsk</p></bio><email xlink:type="simple">kodemeshko@mznso.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Государственный Новосибирский областной клинический госпиталь ветеранов войн</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Novosibirsk Regional Clinical Hospital of War Veterans</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Новосибирский государственный медицинский университет; Новосибирский научно-исследовательский институт гигиены</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University; Novosibirsk Scientific Research Institute of Hygiene</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Новосибирский государственный медицинский университет; Научно-исследовательский институт терапии и профилактической медицины – филиал Федерального исследовательского центра Институт цитологии и генетики СО РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University; Research Institute of Therapy and Preventive Medicine – Branch of the Federal Research Center Institute of Cytology and Genetics SB RAS</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>01</day><month>01</month><year>2023</year></pub-date><volume>13</volume><issue>4</issue><fpage>22</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Golovko E.A., Nessina I.A., Smirnova E.L., Poteruaeva E.L., Figurenko N.N., Demeshko K.O., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Головко Е.А., Несина И.А., Смирнова Е.Л., Потеряева Е.Л., Фигуренко Н.Н., Демешко К.О.</copyright-holder><copyright-holder xml:lang="en">Golovko E.A., Nessina I.A., Smirnova E.L., Poteruaeva E.L., Figurenko N.N., Demeshko K.O.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medicalherald.ru/jour/article/view/1706">https://www.medicalherald.ru/jour/article/view/1706</self-uri><abstract><p>Objective: to analyze the results of periodic medical examinations of employees of a large medical organization in dynamics, according to the final acts. Materials and methods: the research material was the final acts (2019–2021), compiled based on the results of periodic medical examinations of employees of the Novosibirsk Regional Clinical Hospital of War Veterans (Novosibirsk Regional Clinical Hospital of War Veterans). For the analysis, data on the structure of diseases for 2019–2021 were also used, with which medical workers underwent treatment courses in the day hospital of the hospital. Results: in just 3 years, 546 hospital employees under-went periodic medical examination, 489 of them women. The results of the studies have shown that in the dynamics of three-year follow-up, the number of persons subject to additional examination, treatment and dispensary observation has sharply increased, which may indicate a certain effectiveness of PMT. The detectability of chronic somatic diseases according to the results of the PMT has increased by more than 10 times in dynamics. 69 medical workers underwent treatment courses on the basis of the GNOCGV day hospital for 3 years. Of these, 22 medical workers were treated and rehabilitated in a day hospital with the consequences of a new COVID-19 coronavirus infection. Conclusion: when analyzing the final acts based on the results of the PMOS of GNOCGV employees for the period from 2019 to 2021, it was found that the efficiency and quality of inspections has increased dramatically.</p></abstract><trans-abstract xml:lang="ru"><p>Цель: провести анализ результатов периодических медицинских осмотров работников крупной медицинской организации в динамике по данным заключительных актов. Материалы и методы: материалом исследования послужили заключительные акты (2019–2021 гг.), составленные по результатам проведения периодических медицинских осмотров сотрудников ГБУЗ НСО «Государственный Новосибирский областной клинический госпиталь ветеранов войн» (ГБУЗ НСО ГНОКГВВ). Для анализа также были использованы данные о структуре заболеваний за 2019–2021 гг., с которыми медицинские работники проходили курсы лечения в дневном стационаре госпиталя. Результаты: всего за 3 года периодический медицинский осмотр прошли 546 сотрудников госпиталя, из них 489 женщин. Результаты исследований показали, что в динамике трёхлетнего наблюдения резко увеличилось количество лиц, подлежащих дополнительному обследованию, лечению и диспансерному наблюдению, что может свидетельствовать об определённой эффективности ПМО. Выявляемость хронических соматических заболеваний, по результатам проведения ПМО, в динамике увеличилась более чем в 10 раз. На базе дневного стационара ГНОКГВВ за 3 года 69 медицинских работников прошли курсы лечения. Из них 22 медицинских работника проходили лечение и реабилитацию в условиях дневного стационара с последствиями перенесённой новой коронавирусной инфекции COVID-19. Заключение: при анализе заключительных актов, по результатам проведения ПМО сотрудников ГНОКГВВ, за период с 2019 по 2021 гг. было обнаружено, что в динамике увеличилось количество выявленных лиц, нуждающихся в дообследовании, лечении и диспансерном наблюдении. Также за трёхлетний период наблюдения более чем в 10 раз выросла выявляемость хронических соматических заболеваний у медицинских работников, что позволяет снизить как количество профессиональных заболеваний, так и прогрессирование общих заболеваний до тяжёлых форм с инвалидизацией пациентов.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>периодические медицинские осмотры</kwd><kwd>медицинские работники</kwd><kwd>профилактика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>periodic medical examinations</kwd><kwd>medical workers</kwd><kwd>prevention</kwd></kwd-group></article-meta></front><body><sec><title>Introduction</title><p>At present, certain successes have been achieved in the field of labor protection of health workers, but despite this, there is still no single organizational system of occupational safety, which would include scientific research on these problems [<xref ref-type="bibr" rid="cit1">1</xref>].</p><p>Hygienists who exercise external control over working conditions, as well as the authorities of healthcare organizations, do not pay due attention to the occupational safety and health of medical staff, underestimating the degree of danger of the hospital environment as an occupational risk factor. The doctors and nurses themselves do not, probably, attach much importance to solving this problem because traditionally the health maintenance policy was performed mainly for patients, and not for employees. The lack of attention to their health can also be explained by the fact that they are considered to be professionals who are able to take care of their health without anyone's help [<xref ref-type="bibr" rid="cit2">2</xref>]. Meanwhile, health workers are unfairly assigned to the most favorable group in terms of working conditions [<xref ref-type="bibr" rid="cit3">3</xref>]. When studying the health status of health workers, high rates of morbidity, high mortality, and low life expectancy were revealed. One of the reasons for such consequences might be a more severe course and poor prognosis of diseases in health workers, which might be associated with certain features of the health profession [<xref ref-type="bibr" rid="cit4">4</xref>][<xref ref-type="bibr" rid="cit5">5</xref>][<xref ref-type="bibr" rid="cit6">6</xref>]. At present, there are no clear rules or recommendations on occupational safety applicable to all aspects of work in healthcare organizations, and most of the existing recommendations are nonspecific. Regardless of the specialization of hospitals, there are common unfavorable factors of the working environment, such as neuro-emotional stress, chemicals, biological agents, high voltage of analyzer systems, the possibility of injury, and the daily work schedule that disrupt the biological rhythm [<xref ref-type="bibr" rid="cit7">7</xref>].</p><p>The system of preliminary and periodic medical examinations (PMEs) plays a crucial role in the health maintenance of medical staff. One of the main efficiency criteria of preventive medical examinations is the number of detected diseases, both occupational and general ones [<xref ref-type="bibr" rid="cit8">8</xref>].</p><p>The research was aimed at the analysis of the PME results of employees of a large healthcare organization in dynamics, according to the final acts.</p></sec><sec><title>Materials and methods</title><p>The research studied the final acts (2019–2021) compiled based on the PME results of employees of the State Budgetary Institution of Healthcare of the Novosibirsk Region "State Novosibirsk Regional Clinical Hospital for War Veterans". Data on the structure of diseases for 2019–2021, which health workers treated in the day hospital, were also analyzed.</p><p>PMEs were performed at the basis on State Novosibirsk Regional Clinical Hospital for War Veterans in 2019 and 2020 in accordance with the Order of the Ministry of Health and Social Development of the Russian Federation dated April 12, 2011 No. 302n (as amended on May 18, 2020) “On approving the lists of hazardous and (or) dangerous occupational factors and works that require mandatory preliminary and periodic medical examinations (workup) and on Regimen of mandatory preliminary and periodic medical examinations (workup) for workers exposed to intense labor and to hazardous and (or) dangerous work conditions”. In 2021, PMEs were performed in accordance with the Order No. 29n “On approval of the Regimen of mandatory preliminary and periodic medical examinations for workers as provided for by part four of article 213 of the Labor Code of the Russian Federation, the List of medical contraindications for work with hazardous and (or) dangerous occupational factors and works that require mandatory preliminary and periodic medical examinations (workup)” dated January 28, 2021.</p></sec><sec><title>Results</title><p>In just three years, 546 employees underwent PMEs, of which 489 were women. Data based on the results of the analysis of the final acts in dynamics for 2019–2021 are presented in Table 1.</p><table-wrap id="table-1"><caption><p>Table 1</p><p>Dynamics of PME results for 2019–2021</p></caption><table><tbody><tr><td>Categories of surveyed</td><td>Years</td></tr><tr><td>2019</td><td>2020</td><td>2021</td></tr><tr><td>Number of employees of organizations (enterprises) who underwent periodic medical examinations in the reporting year</td><td> </td><td> </td><td> </td></tr><tr><td>Total</td><td>173</td><td>181</td><td>192</td></tr><tr><td>Including women</td><td>160</td><td>163</td><td>166</td></tr><tr><td>Number of persons requiring additional examination</td><td>0</td><td>0</td><td>43</td></tr><tr><td>Number of persons requiring outpatient examination and treatment</td><td>11</td><td>22</td><td>43</td></tr><tr><td>Number of persons requiring inpatient examination and treatment</td><td>0</td><td>4</td><td>3</td></tr><tr><td>The number of persons in need of sanatorium treatment</td><td>0</td><td>36</td><td>125</td></tr><tr><td>Number of persons in need of regular medical checkup</td><td>0</td><td>0</td><td>110</td></tr></tbody></table></table-wrap><p>As Table 1 shows, in 2019, according to the PME results, no persons were identified who needed additional examination, inpatient and sanatorium treatment, as well as a regular medical checkup. Eleven people, i.e., only 6% of the total number of those examined, were identified who needed outpatient treatment. In 2020, 22 people (12%) needed outpatient treatment, 4 people (2%) – inpatient examination and treatment, and 36 people (20%) – sanatorium treatment. In 2021, the situation changed dramatically. The group of people in need of additional outpatient examination and treatment amounted to 43 people (22%), in need of inpatient examination and treatment – 3 people (1.6%), in need of sanatorium treatment – 125 people (65%), and in need of regular medical checkup – 110 people (57%).</p><p>The research results have demonstrated that in the dynamics of a three-year observation, the number of persons who could be subject to additional examination, treatment, and a regular medical checkup has sharply increased, which might indicate a certain PME efficiency.</p><p>In the next stage, the structure of newly diagnosed chronic somatic diseases in dynamics for 2019–2021 was analyzed. The results are presented in Table 2.</p><p>If general morbidity with a temporary disability is considered, then a health worker (primarily a doctor) often does not record it in the relevant documentation, which is why it does not fall into the statistical data. In case of chronic diseases without disability or with minor impairments that allow them to be engaged in predominantly intellectual work (medical diagnostic process, pharmaceutical activity), doctors do not apply to their colleagues, self-medicate, and do not fall into the general statistics [<xref ref-type="bibr" rid="cit9">9</xref>].</p><table-wrap id="table-2"><caption><p>Table 2</p><p>The dynamics of newly identified chronic somatic diseases according to the PME results in the period from 2019 to 2021</p></caption><table><tbody><tr><td>Diseases</td><td>Years</td></tr><tr><td>2019</td><td>2020</td><td>2021</td></tr><tr><td>Total inspected</td><td>173</td><td>181</td><td>192</td></tr><tr><td>Neoplasms (С00-В48)</td><td>0</td><td>0</td><td>3</td></tr><tr><td>Diseases of the blood, blood-forming organs and certain disorders involving the immune mechanism (D50-D89)</td><td>3</td><td>0</td><td>2</td></tr><tr><td>Diseases of the endocrine system, eating disorders and metabolic disorders (E00-E90)</td><td>0</td><td>1</td><td>15</td></tr><tr><td>Diseases of the eye and its adnexa (H90-H95)</td><td>0</td><td>1</td><td>6</td></tr><tr><td>Circulatory diseases (I00-I99)</td><td>1</td><td>1</td><td>2</td></tr><tr><td>Diseases of the digestive system (K00-K93)</td><td>0</td><td> </td><td>3</td></tr><tr><td>Total</td><td>4</td><td>3</td><td>31</td></tr></tbody></table></table-wrap><p>Table 2 shows that in 2019–2020, there was an extremely low detection rate of chronic somatic diseases, according to the PME results. So, in 2019, it was 2%, in 2020 – 1.7%, and in 2021 – 16%, which was 10 times more than in previous years. In the structure of newly diagnosed chronic somatic diseases, diseases of the endocrine system, eating disorders, and metabolic disorders predominated.</p><p>The program for the prevention and rehabilitation of doctors, along with the PME system, includes the organization and provision of preventive treatment in a day hospital.</p><p>Trufanova and Poteryaeva (2018) [<xref ref-type="bibr" rid="cit10">10</xref>], when questioning doctors of a large multidisciplinary hospital, revealed the main measures for improving the organization of medical care for them: 75.4% of doctors noted preventive treatment at the workplace two times a year, 68.8% indicated provision of the possibility of rehabilitation treatment on the basis of the physiotherapy department; 70.7% noted formation of specialized district offices and specialized receptions for unscheduled visits of health workers; 56.2% of doctors positively assessed the creation of a psychological relief room, the possibility of individual psychological correction and group psychological consultations.</p><p>Sixty-nine health workers underwent treatment on the basis of the day hospital of State Novosibirsk Regional Clinical Hospital for War Veterans over 3 years. The structure of diseases over a three-year period is presented in Table 3.</p><table-wrap id="table-3"><caption><p>Table 3</p><p>The structure of diseases of the day hospital of State Novosibirsk Regional Clinical Hospital for War Veterans for the period 2019–2021</p></caption><table><tbody><tr><td>Diagnosis</td><td>Years</td></tr><tr><td>2019</td><td>2020</td><td>2021</td></tr><tr><td>T 91.9 –Sequelae of unspecified injury to neck and trunk</td><td>2</td><td>9</td><td>5</td></tr><tr><td>G 90.8 –Other disorders of the autonomic [autonomous] nervous system</td><td>3</td><td>2</td><td>8</td></tr><tr><td>I 11.9 –Hypertensive [hypertensive] heart disease without (congestive) heart failure</td><td>1</td><td>1</td><td>2</td></tr><tr><td>T 92 –Consequences of injuries of the upper limb</td><td>1</td><td>0</td><td> </td></tr><tr><td>T 93.9 –Sequelae of unspecified lower limb injury</td><td>1</td><td>0</td><td>2</td></tr><tr><td>J 12.8 –Other viral pneumonia</td><td>0</td><td>6</td><td>0</td></tr><tr><td>U 09.9 –Condition after COVID-19, unspecified</td><td>0</td><td>0</td><td>22</td></tr><tr><td>M 54.2 –Cervicalgia</td><td>0</td><td>0</td><td>1</td></tr><tr><td>I 67.9 –Cerebrovascular disease, unspecified</td><td>0</td><td>0</td><td>2</td></tr><tr><td>J 12.9 –Viral pneumonia, unspecified</td><td>0</td><td>0</td><td>1</td></tr><tr><td>Total</td><td>8</td><td>18</td><td>43</td></tr></tbody></table></table-wrap><p>The presented table demonstrates the dynamics of a sharp increase in the number of health workers who underwent treatment and rehabilitation in a day hospital, mainly due to patients with the consequences of a new coronavirus infection COVID-19.</p></sec><sec><title>Conclusion</title><p>When analyzing the final acts of employees of the State Novosibirsk Regional Clinical Hospital for War Veterans based on the PME results for the period from 2019 to 2021, it has been found that the efficiency and quality of examination have increased dramatically. In dynamics, the number of persons who needed additional examination, treatment, and a regular medical checkup has increased. Also, over a three-year follow-up period, the detection rate of chronic somatic diseases in health workers increased by more than 10 times. This was the reason for sending employees for medical examination and treatment in a day hospital. The number of health workers who have been examined and treated in the day hospital of the State Novosibirsk Regional Clinical Hospital for War Veterans has increased over a three-year follow-up period by more than 5 times.</p><p>Early detection of the first signs of occupational and somatic diseases at the stage of PME, their treatment in a day hospital can reduce both the number of occupational diseases and the progression of general diseases to severe forms with disability of patients.</p><p>Authors’ contribution:</p><p>E.A. Golovko, E.L. Poteryaeva — research design development;</p><p>I.A. 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