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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mvjr</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский вестник Юга России</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Herald of the South of Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2219-8075</issn><issn pub-type="epub">2618-7876</issn><publisher><publisher-name>The Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2219-8075-2019-10-1-13-19</article-id><article-id custom-type="elpub" pub-id-type="custom">mvjr-858</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Хирургическая реваскуляризация миокарда с использованием левой внутренней грудной артерии у пациентов с сахарным диабетом</article-title><trans-title-group xml:lang="en"><trans-title>Surgical myocardial revascularization using the left internal thoracic artery in patients with diabetes mellitus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гуснай</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gusnay</surname><given-names>Mikhail V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач сердечно-сосудистый хирург кардиохирургического отделения № 2 кардиохирургического центра;</p><p>врач-аспирант по сердечно-сосудистой хирургии кафедры хирургических болезней ФПК и ППС, ассистент кафедры хирургических болезней ФПК и ППС</p></bio><bio xml:lang="en"><p>cardiovascular surgeon doctor of the cardiac surgery department No. 2</p><p>assistant doctor for cardiovascular surgery of the department of surgical diseases FPK and PPS</p></bio><email xlink:type="simple">mgusnai@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Поддубный</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Poddubny</surname><given-names>Andrey V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., заведующий кардиохирургического отделения №2 кардиохирургического центра</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дюжиков</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dyuzhikov</surname><given-names>Alexander A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н, проф., директор кардиохирургического центра</p><p>профессор кафедры хирургических болезней ФПК и ППС</p></bio><bio xml:lang="en"><p>MD, Professor Director of the Cardiac Surgery Center;</p><p>Professor Department of Surgical Diseases FPK and PPS</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУ РО "Ростовская областная клиническая больница", кардиохирургический центр;&#13;
&#13;
ФГБОУ ВО Ростовский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov Regional Clinical Hospital;&#13;
Rostov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУ РО "Ростовская областная клиническая больница", кардиохирургический центр</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>Rostov Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>02</day><month>04</month><year>2019</year></pub-date><volume>10</volume><issue>1</issue><fpage>13</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гуснай М.В., Поддубный А.В., Дюжиков А.А., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Гуснай М.В., Поддубный А.В., Дюжиков А.А.</copyright-holder><copyright-holder xml:lang="en">Gusnay M.V., Poddubny A.V., Dyuzhikov A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medicalherald.ru/jour/article/view/858">https://www.medicalherald.ru/jour/article/view/858</self-uri><abstract><sec><title>Цель</title><p>Цель: оценить ближайшие и несколько отдаленные результаты хирургической реваскуляризации с использованием левой внутренней грудной артерии у пациентов с сахарным диабетом, сравнить с результатами аутовенозного коронарного шунтирования, выявить возможные осложнения при использовании левой внутренней грудной артерии у пациентов с сахарным диабетом. Материалы и методы: были отобраны 2 группы пациентов, которым с 2010 по 2012 гг. выполняли коронарное шунтирование. У всех пациентов регистрировался сахарный диабет II типа. В первой группе всегда использовали маммарокоронарное шунтирование. Во второй группе маммарокоронарное шунтирование по разным причинам не выполнялось. Результаты: оценивали показатели через 1 год и через 6 лет. В ближайшем послеоперационном периоде отмечено снижение класса стенокардии в обеих группах. Значимого различия в нарушении заживления грудины не наблюдалось. В отдаленном периоде в группе, где выполнялось маммарокоронарное шунтирование, отмечены более низкая летальность, меньший класс стенокардии и меньший процент осложнений со стороны сердечно-сосудистой системы. Выводы: у пациентов, имеющих мультифокальное поражение коронарного русла и сопутствующий сахарный диабет, предпочтительным методом шунтирования коронарных артерий является маммарокоронарное шунтирование, которое может быть дополнено аортокоронарным шунтированием. Это подтверждают данные шестилетнего наблюдения. Левая внутренней грудной артерией может быть смело использована при сахарным диабетом и особенно при стволовом поражении левая коронарная артерия. Проблем с заживлением грудины при бережном выделении левой внутренней грудной артерии не отмечено.</p></sec><sec><title>Конфликт интересов</title><p>Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.</p></sec></abstract><trans-abstract xml:lang="en"><p>Objective: to evaluate the immediate and somewhat distant results of surgical revascularization using the left MKA in patients with diabetes, compared with the results of autovenous CABG, to identify possible complications when using the left MA in patients with diabetes. Materials and methods: 2 groups of patients who, from 2010 to 2012, were selected. performed artery bypass surgery. All patients had type II diabetes. In the first group, the mammaro-coronary artery bypass surgery (MBS) was always used, in the second group and was not performed for various reasons. Results: evaluated indicators aft er 1 year and 6 years. In the immediate postoperative period, we noted a decrease in the class of angina in both groups. We did not observe a significant difference in the violation of the healing of the sternum. In the long-term period, in the group where MBS was performed, we noted a lower mortality rate, a lower class of angina pectoris and a smaller percentage of complications in the cardiovascular system. Conclusions: In patients with multifocal lesions of the coronary bed and concomitant diabetes, the preferred method of coronary artery bypass surgery is MBS, which can be supplemented with CABG. This is confirmed by sixyear observation. MKA can be safely used in diabetes and especially in the stem lesion of the left lance. Problems with the healing of the sternum with careful allocation of LMA we have not noted.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>коронарная хирургия</kwd><kwd>маммарокоронарное шунтирование</kwd><kwd>сахарный диабет</kwd><kwd>ишемическая болезнь сердца</kwd></kwd-group><kwd-group xml:lang="en"><kwd>coronary surgery</kwd><kwd>mammaro-coronary bypass surgery</kwd><kwd>diabetes mellitus</kwd><kwd>coronary heart disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ford E.S., Ajani U.A., Croft J.B., Critchley J.A., Labarthe D.R. et al. Explanation of decrease in US deaths from coronary heart disease, 1980-2000. // N Engl J Med. - 2007. - №356. – P.2388- 2398. DOI: 10.1056/NEJMsa053935</mixed-citation><mixed-citation xml:lang="en">Ford ES, Ajani UA, Croft JB, Critchley JA, Labarthe DR, et al. Explanation of decrease in US deaths from coronary heart disease, 1980-2000. N Engl J Med. 2007;356:2388- 2398. DOI: 10.1056/NEJMsa053935</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И.И., Шестакова М.В., Викулова О.К. Государственный регистр сахарного диабета в Российской Федерации: статус 2014 г. и перспективы развития // Сахарный диабет. - 2015. - № 3. - С. 5-23.</mixed-citation><mixed-citation xml:lang="en">Dedov II, Shestakova MV, Vikulova ОK. Th e State Register of Diabetes in the Russian Federation: Status 2014 and Development Prospects. Diabetes. 2015;3:5-23. (in Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Сахарный диабет 2-го типа: от теории к практике. Под ред. И.И. Дедова, М.В. Шестаковой. - М.: МИА, 2016.</mixed-citation><mixed-citation xml:lang="en">Dedova II, Shestakova MV. eds. Diabetes mellitus type 2: from theory to practice. Moscow: MIA, 2016. (in Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Соколов Е.И. Диабетическое сердце. - Москва, “Медицина” 2002</mixed-citation><mixed-citation xml:lang="en">Sokolov EI. Diabetic heart. Moscow: Medicine; 2002. (in Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ryden L., Standl E., Bartnik M., Van den Berghe G., Betteridge J. et al. Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD) // Eur. Heart J. – 2007. – Vol. 28. – P. 88–136. DOI: 10.1093/eurheartj/ehl260</mixed-citation><mixed-citation xml:lang="en">Rydén L, Standl E, Bartnik M, Van den Berghe G, Betteridge J, et al. Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. Th e European Union of Cardiology (ESC) and the European Association for the Study of Diabetes (EASD). Eur. Heart J. 2007;28(1):88-136. DOI: 10.1093/eurheartj/ehl260</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Акчурин Р.С. 50 лекций по хирургии. Хирургическое лечение ишемической болезни сердца – история и современность. - Media-medica, 2007.</mixed-citation><mixed-citation xml:lang="en">Akchurin RS. 50 lectures on surgery. Surgical treatment of coronary heart disease - history and modernity. Media medica; 2007. (in Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И.И., Терёхин С.А. Реваскуляризация миокарда у больных сахарным диабетом. // Сахарный диабет. – 2010. - №4. – С.18-21.</mixed-citation><mixed-citation xml:lang="en">Dedov II, Terékhin SA. Myocardial revascularization in patients with diabetes mellitus. Diabetes. 2010;4:18-21 (in Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Жбанов И.В., Минкина С.М., Самойленко М.В., Шабалкин Б.В. Аутоартериальные трансплантаты для реваскуляризации миокарда и их морфологическая оценка у больных ишемической болезнью сердца. // Хирургия. – 1996ю - №3. – С.38-40.</mixed-citation><mixed-citation xml:lang="en">Zhbanov IV, Minkina SM, Samoilenko MV, Shabalkin BV. Autoarterial graft s for myocardial revascularization and their morphological evaluation in patients with ischemic heart disease. Surgery. 1996;3:38-40. (in Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Stratton I.M., Adler A.I., Neil H.A., Matthews D.R., Manley S.E., et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective, observational study. // BMJ. – 2000. – V.321(7258). – P.405-12.</mixed-citation><mixed-citation xml:lang="en">Stratton IM, Adler AI, Neil HA, Matthews DR, Manley SE, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective, observational study. BMJ. 2000;321(7258):405-12.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Yilmaz M.B., Guray U., Guray Y., Altay H., Demirkan B., et al. Metabolic syndrome is associated with extension of coronary artery disease in patients with non-ST segment // Coron Artery Dis. – 2005. – V.16(5). – P.287-92.</mixed-citation><mixed-citation xml:lang="en">Yilmaz MB, Guray U, Guray Y, Altay H, Demirkan B, et al. Metabolic syndrome is associated with extension of coronary artery disease in patients with non-ST segment. Coron Artery Dis. 2005;16(5):287-92.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) // JAMA. – 2001. – V.285(19). – P.2486-97.</mixed-citation><mixed-citation xml:lang="en">Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA. 2001;285(19):2486-97.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Hlatky M.A., Boothroyd D.B., Bravata D.M., Boersma E., Booth J., et al. Coronary artery bypass surgery compared with percutaneous coronary interventions for multivessel disease: a collaborative analysis of individual patient data from ten randomised trials // Lancet. – 2009. – Vol. 373. – P. 1190– 1197. doi: 10.1016/S0140-6736(09)60552-3.</mixed-citation><mixed-citation xml:lang="en">Hlatky MA, Boothroyd DB, Bravata DM, Boersma E, Booth J, et al. Coronary artery bypass surgery compared with percutaneous coronary interventions for multivessel disease: a collaborative analysis of individual patient data from ten randomised trials. Lancet. 2009;373(9670):1190-7. doi: 10.1016/S0140-6736(09)60552-3.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Taggart D.P., D’Amico R., Altman D.G. Eff ect of arterial revascularisation on survival: a systematic review of studies comparing bilateral and single internal mammary arteries // Lancet. – 2001. – Vol. 358. – P. 870–875. DOI: 10.1016/S0140- 6736(01)06069-X</mixed-citation><mixed-citation xml:lang="en">Taggart DP, D’Amico R, Altman DG. Eff ect of arterial revascularisation on survival: a systematic review of studies comparing bilateral and single internal mammary arteries. Lancet. 2001;358(9285):870-5. DOI: 10.1016/S0140- 6736(01)06069-X</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Berger A., MacCarthy P.A., Siebert U., Carlier S., Wijns W., et al. Long-term patency of internal mammary artery bypass grafts: relationship with preoperative severity of the native coronary artery stenosis. // Circulation. – 2004. – V.110(11 Suppl 1). – P.II36-40. DOI: 10.1161/01.CIR.0000141256.05740.69</mixed-citation><mixed-citation xml:lang="en">Berger A, MacCarthy PA, Siebert U, Carlier S, Wijns W, et al. Long-term patency of internal mammary artery bypass graft s: relationship with preoperative severity of the native coronary artery stenosis. Circulation. 2004;110(11 Suppl 1):II36-40. DOI: 10.1161/01.CIR.0000141256.05740.69</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Kappetein A.P., Dawkins K.D., Mohr F.W., Morice M.C., Mack M.J. et al. Current percutaneous coronary intervention and coronary artery bypass graft ing practices for three-vessel and left main coronary artery disease. Insights from the SYNTAX run-in phase. // Eur J Cardiothorac Surg. – 2006. – V.29(4). – P.486-91. DOI: 10.1016/j.ejcts.2006.01.047</mixed-citation><mixed-citation xml:lang="en">Kappetein AP, Dawkins KD, Mohr FW, Morice MC, Mack MJ et al.  Current percutaneous coronary intervention and coronary artery bypass graft ing practices for three-vessel and left main coronary artery disease. Insights from the SYNTAX run-in phase.  Eur J Cardiothorac Surg. 2006;29(4):486-91. DOI: 10.1016/j.ejcts.2006.01.047</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Schmitto J.D., Rajab T.K., Cohn L.H. Prevalence and variability of internal mammary graft use in contemporary multivessel coronary artery bypass graft . // Curr Opin Cardiol. – 2010. – V.25(6). – P.609-12. doi: 10.1097/HCO.0b013e32833f0498.</mixed-citation><mixed-citation xml:lang="en">Schmitto JD, Rajab TK, Cohn LH. Prevalence and variability of internal mammary graft use in contemporary multivessel coronary artery bypass graft . Curr Opin Cardiol. 2010;25(6):609-12. doi: 10.1097/HCO.0b013e32833f0498.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Calafi ore A.M., Di Mauro M., Di Giammarco G., Contini M., Vitolla G. et al. Eff ect of diabetes on early and late survival aft er isolated fi rst coronary bypass surgery in multivessel disease. // J Th orac Cardiovasc Surg. – 2003. – V.125(1). – P.144-54. DOI: 10.1067/mtc.2003.73</mixed-citation><mixed-citation xml:lang="en">Calafi ore AM, Di Mauro M, Di Giammarco G, Contini M, Vitolla G et al. Eff ect ofdiabetes on early and late survival aft er isolated fi rst coronary bypass surgery in multivessel disease. J Th orac Cardiovasc Surg. 2003;125(1):144-54. DOI: 10.1067/ mtc.2003.73</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Berry C., Tardif J., Bourassa M. Coronary heart disease in patients with diabetes: part I: recent advances in prevention and noninvasive management // J. Am. Coll. Cardiol. – 2007. – Vol. 49. – P. 631–642. DOI: 10.1016/j.jacc.2006.09.046</mixed-citation><mixed-citation xml:lang="en">Berry C., Tardif J., Bourassa M. Coronary heart disease in patients with diabetes: part I: recent advances in prevention and noninvasive management. J Am Coll Cardiol. 2007;49(6):631- 42. DOI: 10.1016/j.jacc.2006.09.046</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Hirotani T., Kameda T., Kumamoto T., Shirota S., Yamano M. Eff ects of coronary artery bypass graft ing using internal mammary arteries for diabetic patients. // J Am Coll Cardiol. – 1999. – V.34(2). – P.532-8.</mixed-citation><mixed-citation xml:lang="en">Hirotani T, Kameda T, Kumamoto T, Shirota S, Yamano M. Eff ects of coronary artery bypass graft ing using internal mammary arteries for diabetic patients. J Am Coll Cardiol. 1999;34(2):532-8.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Carson J.L., Scholz P.M., Chen A.Y., Peterson E.D., Gold J., Schneider S.H. Diabetes mellitus increases shortterm mortality and morbidity in patients undergoing coronary artery bypass graft surgery. // J Am Coll Cardiol. – 2002. – V.40(3). – P.418-23.</mixed-citation><mixed-citation xml:lang="en">Carson JL, Scholz PM, Chen AY, Peterson ED, Gold J, Schneider SH. Diabetes mellitus increases shortterm mortality and morbidity in patients undergoing coronary artery bypass graft surgery. J Am Coll Cardiol. 2002;40(3):418-23.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
