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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mvjr</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский вестник Юга России</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Herald of the South of Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2219-8075</issn><issn pub-type="epub">2618-7876</issn><publisher><publisher-name>The Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2219-8075-2018-9-2-51-60</article-id><article-id custom-type="elpub" pub-id-type="custom">mvjr-665</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Влияние нейрогенной хронической боли на показатели калликреин-кининовой системы в коже самок мышей в динамике развития меланомы В16/F10</article-title><trans-title-group xml:lang="en"><trans-title>Inﬂ uence of neurogenic chronic pain on indicators of kallikreinkinin system in skin of female mice in dynamics of В16/F10 melanoma development</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3061-6108</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кит</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kit</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кит Олег Иванович, член-корр. РАН, д.м.н., профессор, генеральный директор.</p><p>Ростов-на-Дону.</p></bio><bio xml:lang="en"><p>Oleg I. Kit, corresponding member. RAS, Doctor of Medicine, Professor, General Director.</p><p>Rostov-on-Don.</p></bio><email xlink:type="simple">onkosekretar@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3972-2452</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котиева</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotieva</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Котиева Инга Мовлиевна, к.м.н., доцент кафедры патологической физиологии.</p><p>Ростов-на-Дону.</p></bio><bio xml:lang="en"><p>Inga M. Kotieva, PhD, Rostov State Medical University.</p><p>Rostov-on-Don.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3618-6890</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Франциянц</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Frantsiyants</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Франциянц Елена Михайловна, д.б.н., профессор, заместитель генерального директора по науке.</p><p>Ростов-на-Дону.</p></bio><bio xml:lang="en"><p>Elena M. Frantsiyants, Doctor of Biological Sciences, Professor, Deputy Director General for Science.</p><p>Rostov-on-Don.</p></bio><email xlink:type="simple">super.gormon@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3972-2452</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каплиева</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaplieva</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каплиева Ирина Викторовна, к.м.н., старший научный сотрудник.</p><p>Ростов-на-Дону.</p></bio><bio xml:lang="en"><p>Irina V. Kaplieva, PhD.</p><p>Rostov-on-Don.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3907-0976</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козлова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlova</surname><given-names>L. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Козлова Лариса Степановна, к.б.н., доцент, старший научный сотрудник.</p><p>Ростов-на-Дону.</p></bio><bio xml:lang="en"><p>Larisa S. Kozlova, PhD.</p><p>Rostov-on-Don.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2302-8271</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бандовкина</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bandovkina</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бандовкина Валерия Ахтямовна, к.б.н., старший научный сотрудник.</p><p>Ростов-на-Дону.</p></bio><bio xml:lang="en"><p>Valeria A. Bandovkina, PhD.</p><p>Rostov-on-Don.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2674-9832</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Погорелова</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pogorelova</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Погорелова Юлия Александровна, к.б.н., старший научный сотрудник.</p><p>Ростов-на-Дону.</p></bio><bio xml:lang="en"><p>Yulia A. Pogorelova, PhD.</p><p>Rostov-on-Don.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3711-8155</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черярина</surname><given-names>Н. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Cheryarina</surname><given-names>N. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Черярина Наталья Дмитриевна, врач лаборант.</p><p>Ростов-на-Дону.</p></bio><bio xml:lang="en"><p>Natalya D. Cheryarina, Rostov Research Institute of Oncology.</p><p>Rostov-on-Don.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бликян</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Blikyan</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бликян Марина Владимировна, к.м.н., ассистент кафедры патологической физиологии.</p><p>Ростов-на-Дону.</p></bio><bio xml:lang="en"><p>Marina V. Blikyan, PhD.</p><p>Rostov-on-Don.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ростовский научно-исследовательский онкологический институт.</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov Research Institute of Oncology.</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Ростовский государственный медицинский университет.</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>Rostov State Medical University.</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>09</day><month>06</month><year>2018</year></pub-date><volume>9</volume><issue>2</issue><fpage>51</fpage><lpage>60</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кит О.И., Котиева И.М., Франциянц Е.М., Каплиева И.В., Козлова Л.С., Бандовкина В.А., Погорелова Ю.А., Черярина Н.Д., Бликян М.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Кит О.И., Котиева И.М., Франциянц Е.М., Каплиева И.В., Козлова Л.С., Бандовкина В.А., Погорелова Ю.А., Черярина Н.Д., Бликян М.В.</copyright-holder><copyright-holder xml:lang="en">Kit O.I., Kotieva I.M., Frantsiyants E.M., Kaplieva I.V., Kozlova L.S., Bandovkina V.A., Pogorelova Y.A., Cheryarina N.D., Blikyan M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medicalherald.ru/jour/article/view/665">https://www.medicalherald.ru/jour/article/view/665</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>меланома</kwd><kwd>хроническая нейрогенная боль</kwd><kwd>кининовая система</kwd></kwd-group><kwd-group xml:lang="en"><kwd>melanoma</kwd><kwd>chronic neurogenic pain</kwd><kwd>kinin system</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">1Федеральное государственное бюджетное учреждение «Ростовский научно-исследовательский онкологический институт» Министерства здравоохранения Российской Федерации. 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