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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mvjr</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский вестник Юга России</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Herald of the South of Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2219-8075</issn><issn pub-type="epub">2618-7876</issn><publisher><publisher-name>The Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2219-8075-2016-4-59-62</article-id><article-id custom-type="elpub" pub-id-type="custom">mvjr-479</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>ПЕРВЫЙ ОПЫТ ПРЯМОЙ ПОСТОЯННОЙ ЭЛЕКТРОКАРДИОСТИМУЛЯЦИИ ПУЧКА ГИСА</article-title><trans-title-group xml:lang="en"><trans-title>FIRST EXPERIENCE OF DIRECT CONSTANT HIS BUNDLE PACING</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чудинов</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chudinov</surname><given-names>G. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>344022, Ростов-на-Дону,  пер Нахичеванский, 29, e-mail: chudinovgeorgy@gmail.com</p></bio><bio xml:lang="en"><p>29 Nakhichevansky st., Rostov-on-Don 344022, Russia</p></bio><email xlink:type="simple">chudinovgeorgy@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черкасов</surname><given-names>М. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Cherkasov</surname><given-names>M. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>344022, Ростов-на-Дону,  пер Нахичеванский, 29, e-mail: chudinovgeorgy@gmail.com</p></bio><bio xml:lang="en"><p>29 Nakhichevansky st., Rostov-on-Don 344022, Russia</p></bio><email xlink:type="simple">chudinovgeorgy@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пономарев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ponomarev</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>344022, Ростов-на-Дону,  пер Нахичеванский, 29, e-mail: chudinovgeorgy@gmail.com</p></bio><bio xml:lang="en"><p>29 Nakhichevansky st., Rostov-on-Don 344022, Russia</p></bio><email xlink:type="simple">chudinovgeorgy@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коршунов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Korshunov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>344022, Ростов-на-Дону,  пер Нахичеванский, 29, e-mail: chudinovgeorgy@gmail.com</p></bio><bio xml:lang="en"><p>29 Nakhichevansky st., Rostov-on-Don 344022, Russia</p></bio><email xlink:type="simple">chudinovgeorgy@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скляров</surname><given-names>Ф. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sklyarov</surname><given-names>F. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>344022, Ростов-на-Дону,  пер Нахичеванский, 29, e-mail: chudinovgeorgy@gmail.com</p></bio><bio xml:lang="en"><p>29 Nakhichevansky st., Rostov-on-Don 344022, Russia</p></bio><email xlink:type="simple">chudinovgeorgy@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каракозов</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Karakozov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>344022, Ростов-на-Дону,  пер Нахичеванский, 29, e-mail: chudinovgeorgy@gmail.com</p></bio><bio xml:lang="en"><p>29 Nakhichevansky st., Rostov-on-Don 344022, Russia</p></bio><email xlink:type="simple">chudinovgeorgy@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Песков</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Peskov</surname><given-names>N. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>344022, Ростов-на-Дону,  пер Нахичеванский, 29, e-mail: chudinovgeorgy@gmail.com</p></bio><bio xml:lang="en"><p>29 Nakhichevansky st., Rostov-on-Don 344022, Russia</p></bio><email xlink:type="simple">chudinovgeorgy@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Татьянченко</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tatyanchenko</surname><given-names>A. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>344022, Ростов-на-Дону,  пер Нахичеванский, 29, e-mail: chudinovgeorgy@gmail.com</p></bio><bio xml:lang="en"><p>29 Nakhichevansky st., Rostov-on-Don 344022, Russia</p></bio><email xlink:type="simple">chudinovgeorgy@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ростовский государственный медицинский университет Россия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>4</issue><fpage>59</fpage><lpage>62</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чудинов Г.В., Черкасов М.Ф., Пономарев А.В., Коршунов В.В., Скляров Ф.В., Каракозов Д.А., Песков Н.А., Татьянченко А.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Чудинов Г.В., Черкасов М.Ф., Пономарев А.В., Коршунов В.В., Скляров Ф.В., Каракозов Д.А., Песков Н.А., Татьянченко А.А.</copyright-holder><copyright-holder xml:lang="en">Chudinov G.V., Cherkasov M.F., Ponomarev A.V., Korshunov V.V., Sklyarov F.V., Karakozov D.A., Peskov N.А., Tatyanchenko A.А.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medicalherald.ru/jour/article/view/479">https://www.medicalherald.ru/jour/article/view/479</self-uri><abstract><p>Цель: изучить электрофизиологические параметры и клинические результаты прямой  стимуляции пучка Гиса. Материал и методы: обследованы 36 пациентов, разделенных на 2 группы (по 18 чел.) по признаку чреспредсердной (первая) или чресжелудочковой (вторая) стимуляции пучка Гиса. В сроки до 12 мес. с момента имплантации оценивались параметры электрокардиостимуляции, данные поверхностной ЭКГ, ультразвуковая динамика размеров полостей сердца, качество жизни по шкале MOSSF-36. Результаты: в первой группе время электрической систолы миокарда желудочков (ширина QRS) оказалось достоверно меньше — 111±13 мсек., по сравнению со второй — 134±19, — что соответствует физиологическому паттерну возбуждения миокарда желудочков, исключает диссинхронию, диастолическую дисфункцию левого желудочка, развитие аритмогенной хронической сердечной недостаточности. Качество жизни пациентов первой группы оказалось достоверно выше (71±8,5) против 63±9,9 баллов у пациентов второй группы. Выводы: имплантация чреспредсердного электрода в область пучка Гиса обеспечивает более надежную фиксацию, меньший риск его дислокации в раннем послеоперационном периоде и облегчает его деимплантацию в случае возникновения соответствующих показаний. Клиническое внедрение данного лечебного подхода послужит импульсом к созданию отечественной промышленностью специального эндокардиального электрода, доставляющего устройства и стимулятора типа DDD(R), имеющего резервный желудочковый канал, что особенно актуально в условиях импортозамещения.</p></abstract><trans-abstract xml:lang="en"><p>Objective: to study electrophysiological parameters and clinical results of direct constant His bundle pacing (HBP). Materials and methods: we examined 36 patients, divided into 2 equal groups (of 18 patients) according to the type of pacing. Group 1 included patients with atrial lead delivery and group 2with ventricle lead delivery. Within 12 months after implantation of the pacemaker were evaluated pacing options, ECG data, changes in heart cavities sizes, quality of life assessments with the MOS SF-36. Results: it turned out that in group 1 QRS duration was 111±13 ms, whereas QRS duration in group 2 was 134±19 ms. So QRS duration and morphology corresponded to physiological and excluded uprising of ventricle dyssynchrony, LV diastolic dysfunction and chronic heart insufficiency, quality of life were higher for group 1 paients : 71±8,5 whereas 63±9,9 in group 2. Conclusions: implantation atrial lead in His-bundle provides more reliable fixation, less early dislocation risk in early postoperative period and facilitates lead extraction. Clinical implementation of this method will contribute Russian industry, which is especially important in import substitution conditions, to the creation of special lead, delivery system and DDDR pacemaker with a backup ventricle channel.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>пучок Гиса</kwd><kwd>электрокардиостимуляция</kwd><kwd>эндокардиальный электрод</kwd></kwd-group><kwd-group xml:lang="en"><kwd>His bundle</kwd><kwd>pacing</kwd><kwd>lead</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lamas GA, Lee KL, Sweeney MO, et al. MOST Investigators Ventricular pacing or dual chamber pacing for sinus node dysfunction. N Engl J Med. 2002;346:1854-1862.</mixed-citation><mixed-citation xml:lang="en">Lamas GA, Lee KL, Sweeney MO, et al. MOST Investigators Ventricular pacing or dual chamber pacing for sinus node dysfunction. N Engl J Med. 2002;346:1854-1862.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Sharma AD, Rizo-Patron C, Hallstrom AP, et al. DAVID Investigators Percent right ventricular pacing predicts outcomes in the DAVID Trial Heart Rhythm 2005;2:830-834.</mixed-citation><mixed-citation xml:lang="en">Sharma AD, Rizo-Patron C, Hallstrom AP, et al. DAVID Investigators Percent right ventricular pacing predicts outcomes in the DAVID Trial Heart Rhythm 2005;2:830-834.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Sweeney MO, Prinzen FW. A new paradigm for physiologic ventricular pacing J Am Coll Cardiol 2006;47:282-288.</mixed-citation><mixed-citation xml:lang="en">Sweeney MO, Prinzen FW. A new paradigm for physiologic ventricular pacing J Am Coll Cardiol 2006;47:282-288.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Victor F, Mabo P, et al. A randomized comparison of permanent septal versus apical right ventricular pacing: short-term results. J Cardiovasc Electrophysiol 2006;17:238–42.</mixed-citation><mixed-citation xml:lang="en">Victor F, Mabo P, et al. A randomized comparison of permanent septal versus apical right ventricular pacing: short-term results. J Cardiovasc Electrophysiol 2006;17:238–42.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">De Cock CC, Giudici MC, Twisk J. Comparison of the haemodynamic effects of right ventricular outflow-tract pacing with right ventricular apex pacinga quantitative review. Europace 2003;5:275-278.</mixed-citation><mixed-citation xml:lang="en">De Cock CC, Giudici MC, Twisk J. Comparison of the haemodynamic effects of right ventricular outflow-tract pacing with right ventricular apex pacinga quantitative review. Europace 2003;5:275-278.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Yee R, Klein GJ, Krahn AC, Skanes AC. Selective site pacing: tools and training. Pacing Clin Electrophysiol 2004;27:894–6.</mixed-citation><mixed-citation xml:lang="en">Yee R, Klein GJ, Krahn AC, Skanes AC. Selective site pacing: tools and training. Pacing Clin Electrophysiol 2004;27:894–6.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Occhetta E, Bortnik M, Magnani A, et al. Prevention of ventricular desynchronization by permanent para-Hisian pacing after atrioventricular node ablation in chronic atrial fibrillation: a crossover, blinded, randomized study versus apical right ventricular pacing. J Am Coll Cardiol 2006;47:1938–45.</mixed-citation><mixed-citation xml:lang="en">Occhetta E, Bortnik M, Magnani A, et al. Prevention of ventricular desynchronization by permanent para-Hisian pacing after atrioventricular node ablation in chronic atrial fibrillation: a crossover, blinded, randomized study versus apical right ventricular pacing. J Am Coll Cardiol 2006;47:1938–45.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Deshmukh P, Casavant DA, Romanyshyn M, Anderson K. Permanent, direct His-bundle pacing: a novel approach to cardiac pacing in patients with normal His-Purkinje activation. Circulation 2000;101: 869–77.</mixed-citation><mixed-citation xml:lang="en">Deshmukh P, Casavant DA, Romanyshyn M, Anderson K. Permanent, direct His-bundle pacing: a novel approach to cardiac pacing in patients with normal His-Purkinje activation. Circulation 2000;101: 869–77.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Lu F, Iaizzo PA, et al. Isolated Atrial Segment Pacing: An Alternative to His Bundle Pacing After Atrioventricular Junctional Ablation. J Am Coll Cardiol 2007;49:1443–9.</mixed-citation><mixed-citation xml:lang="en">Lu F, Iaizzo PA, et al. Isolated Atrial Segment Pacing: An Alternative to His Bundle Pacing After Atrioventricular Junctional Ablation. J Am Coll Cardiol 2007;49:1443–9.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
