mvjrМедицинский вестник Юга РоссииMedical Herald of the South of Russia2219-80752618-7876The Rostov State Medical University10.21886/2219-8075-2015-2-9-14mvjr-239Research ArticleОБЗОРЫREVIEWРОЛЬ ДЕФЕНЗИНОВ В РАЗВИТИИ ПАТОЛОГИЧЕСКОГО ПРОЦЕССА: НОВЫЕ ПОДХОДЫ К ДИАГНОСТИКЕ И ЛЕЧЕНИЮТhe role of defensins in the development of pathologic process: new approaches to diagnosis and treatment (literature review)ДудниковаЭ. В.DudnikovaE. V.alex.badyan@rambler.ruБадьянА. С.BadyanA. S.Ростовский государственный медицинский университет, кафедра детских болезней № 1РоссияRostov State Medical University, Children’s diseases departmentRussian Federation20153006201502914Copyright © Дудникова Э.В., Бадьян А.С., 20152015Дудникова Э.В., Бадьян А.С.Dudnikova E.V., Badyan A.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.medicalherald.ru/jour/article/view/239

В обзоре литературы представлены данные о свойствах и биологическом действии дефензинов, обладающих антибактериальной, противовирусной, противогрибковой, противоопухолевой, провоспалительной активностью, их роли в генезе различных заболеваний, а также новые возможности использования представленных катионных антимикробных пептидов в диагностике и лечении патологических состояний.

This literature review summarises and evaluates existing data about properties and biological activity of defensins, more particularly about their antibacterial, antiviral, antifungal, anticancer, anti-inflammatory activity, their role in the genesis of various diseases, as well as new perspectives for the use of presented cationic antimicrobial peptides in diagnosis and treatmentof different pathologies.

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The authors declare that there are no conflicts of interest present.