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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mvjr</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский вестник Юга России</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Herald of the South of Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2219-8075</issn><issn pub-type="epub">2618-7876</issn><publisher><publisher-name>The Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2219-8075-2025-16-3-22-29</article-id><article-id custom-type="elpub" pub-id-type="custom">mvjr-2039</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКУШЕРСТВО И ГИНЕКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OBSTETRICS AND GYNECOLOGY</subject></subj-group></article-categories><title-group><article-title>Радиологический изолированный синдром в раннем послеродовом периоде (случай из практики)</article-title><trans-title-group xml:lang="en"><trans-title>Radiologic isolated syndrome in the early postpartum period (case report)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8945-4142</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Логинов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Loginov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Логинов Игорь Александрович, к.м.н., доцент, доцент кафедры акушерства и гинекологии № 1</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Igor A. Loginov, Cand. Sci. (Med.), аssociate Professor, аssociate Professor of the Department of оbstetrics and gynecology No. 1</p><p>Rostov-on-Don</p></bio><email xlink:type="simple">Loginovi@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-9970-8384</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борщева</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Borsheva</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Борщева Алла Александровна, к.м.н., доцент, доцент кафедры акушерства и гинекологии № 1</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Alla A. Borsheva, P.h.D, associate Professor, associate Professor of the Department of obstetrics and gynecology No. 1</p><p>Rostov-on-Don</p></bio><email xlink:type="simple">aborsheva@rostov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1645-160X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Латынин</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Latynin</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Латынин Андрей Николаевич, заместитель главного врача по акушерству и гинекологии</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Andrey N. Latynin, the deputy chief physician for obstetrics and gynecology</p><p>Rostov-on-Don</p></bio><email xlink:type="simple">latininandrei@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ростовский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Городская клиническая больница № 20</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City clinical hospital No. 20</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>25</day><month>09</month><year>2025</year></pub-date><volume>16</volume><issue>3</issue><fpage>22</fpage><lpage>29</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Логинов И.А., Борщева А.А., Латынин А.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Логинов И.А., Борщева А.А., Латынин А.Н.</copyright-holder><copyright-holder xml:lang="en">Loginov I.A., Borsheva A.A., Latynin A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medicalherald.ru/jour/article/view/2039">https://www.medicalherald.ru/jour/article/view/2039</self-uri><abstract><p>В настоящее время в практическом здравоохранении используются понятия: радиологический изолированный синдром (РИС) и клинически изолированный синдром (КИС). РИС — это очаги в белом веществе головного мозга, выявляемые на МРТ, которые зачастую интерпретируются как демиелинизирующий процесс и дают возможность предположить наличие у пациентов рассеянного склероза (РС). Указанные изменения не имеют клинических проявлений и неврологических симптомов, характерных для РС. Рассеянный склероз — это хроническое прогрессирующее заболевание центральной нервной системы. РС широко распространён среди женщин репродуктивного возраста, что создает проблемы как для акушеров, так и для неврологов в плане решения вопросов планирования и ведения беременности и родов. Поэтому клиническая и прогностическая значимость указанных изменений у пациентов с РИС остается спорной. Но неопровержимым является тот факт, что пациенты с РИС относятся к группе высокого риска развития РС. Около 2/3 пациентов имеет прогрессирование, по данным МРТ, около 1/3 пациентов — появление клинических симптомов в течение 5 лет наблюдения. В приведённом случае у пациентки развился отдельный клинический эпизод, проявившийся судорожным синдромом в послеродовом (после кесарева сечения) периоде, что дало основание предположить, что это был дебют КИС на фоне имевшего место, но выявленного нами лишь в послеродовом периоде РИС.</p></abstract><trans-abstract xml:lang="en"><p>The terms radiologic isolated syndrome (RIS) and clinically isolated syndrome (CIS) are currently used in practical healthcare. RIS are foci in the white matter of the brain detected on MRI, which are oﬅen interpreted as a demyelinating process and suggest the presence of multiple sclerosis (MS) in patients. These changes do not have clinical manifestations and neurologic symptoms characteristic of MS. Multiple sclerosis (MS) is a chronic progressive disease of the central nervous system. MS is widespread among women of reproductive age, which poses a challenge to both obstetricians and neurologists in terms of addressing the planning and management of pregnancy and childbirth. Therefore, the clinical and prognostic signiﬁcance of these changes in patients with RIS remains controversial. But it is undeniable that patients with RIS are at high risk of developing MS: about 2/3 of patients have progression according to MRI and about 1/3 of patients have clinical symptoms within 5 years of follow-up. In the case that we would like to present to you, a separate clinical episode developed against the background of RIS, manifested by a seizure syndrome in the postpartum (aﬅer cesarean section) period, which suggested that this was the debut of CIP against the background of an existing but undetected RIS. This prompted us to describe this case and present it to researchers and practicing physicians.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>кесарево сечение</kwd><kwd>плод</kwd><kwd>беременность</kwd><kwd>роды</kwd><kwd>радиологческий изолированный синдром</kwd><kwd>клинически изолированный синдром</kwd><kwd>рассеянный склероз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cesarean section</kwd><kwd>fetus</kwd><kwd>pregnancy</kwd><kwd>labor</kwd><kwd>radiologic isolated syndrome (RIS)</kwd><kwd>clinically isolated syndrome (CIS)</kwd><kwd>multiple sclerosis (MS)</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Peng A, Qiu X, Zhang L, Zhu X, He S, et al. Natalizumab exposure during pregnancy in multiple sclerosis: a systematic review. 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