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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mvjr</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский вестник Юга России</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Herald of the South of Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2219-8075</issn><issn pub-type="epub">2618-7876</issn><publisher><publisher-name>The Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2219-8075-2024-15-1-126-140</article-id><article-id custom-type="elpub" pub-id-type="custom">mvjr-1829</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ВНУТРЕННИЕ БОЛЕЗНИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INTERNAL DISEASES</subject></subj-group></article-categories><title-group><article-title>Использование метода искусственных нейронных сетей для интегрирования в систему поддержки принятия решений как инструмент оптимизации амбулаторного ведения пациентов с хронической обструктивной болезнью лёгких</article-title><trans-title-group xml:lang="en"><trans-title>Using the method of artificial neural networks for integration into the decision support system as a tool for optimizing outpatient management of patients with chronic obstructive pulmonary disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5421-4202</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таютина</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tayutina</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Таютина Татьяна Владимировна, к.м.н., доцент кафедры терапии с курсом поликлинической терапии</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Tatiana V. Tayutina, Cand. Sci. (Med.), Associate Professor of the Department of Therapy with a course of Polyclinic Therapy</p><p>Rostov-on-Don</p></bio><email xlink:type="simple">tarus76@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3070-8424</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шлык</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shlyk</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шлык Сергей Владимирович, д.м.н., проф., ректор, заведующий кафедры терапии с курсом поликлинической терапии</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Sergey V. Shlyk, Dr. Sci. (Med.), Professor, Rector, Head of the Department of Therapy with a course of Polyclinic Therapy</p><p>Rostov-on-Don</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8884-968X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Водопьянов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Vodopyanov</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Водопьянов Алексей Сергеевич, ведущий научный сотрудник лаборатории молекулярной биологии природно-очаговых и зоонозных инфекций</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Alexey S. Vodopyanov, Leading Researcher at the Laboratory of Molecular Biology of Natural Focal and Zoonotic Infections</p><p>Rostov-on-Don</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2097-4091</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казарян</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kazaryan</surname><given-names>T. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Казарян Татьяна Михайловна, студентка 5 курса лечебно-профилактического факультета, лаборант кафедры терапии с курсом поликлинической терапии</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Tatiana M. Kazarian, 5th year student of the Faculty of Medical Prevention, laboratory assis-tant of the Department of Therapy with a course of Polyclinic Therapy</p><p>Rostov-on-Don</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ростовский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Ростовский противочумный институт Роспотребнадзора</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>Federal State Health Institution Rostov Anti-Plague Institute of Rospotrebnadzor</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>14</day><month>03</month><year>2024</year></pub-date><volume>15</volume><issue>1</issue><fpage>126</fpage><lpage>140</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Таютина Т.В., Шлык С.В., Водопьянов А.С., Казарян Т.М., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Таютина Т.В., Шлык С.В., Водопьянов А.С., Казарян Т.М.</copyright-holder><copyright-holder xml:lang="en">Tayutina T.V., Shlyk S.V., Vodopyanov A.S., Kazaryan T.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medicalherald.ru/jour/article/view/1829">https://www.medicalherald.ru/jour/article/view/1829</self-uri><abstract><sec><title>Цель</title><p>Цель: оценить возможность использования искусственных нейронных сетей для интегрирования в систему поддержки принятия врачебных решений в качестве оптимизации амбулаторного ведения пациентов с ХОБЛ.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы: проведено динамическое наблюдение 150 пациентов с хронической обструктивной болезнью лёгких, состоящих на диспансерном учёте по основному заболеванию, завершивших амбулаторный этап лёгочной реабилитации после перенесённого обострения средней степени тяжести. Материалом исследования явилась универсальная анкета из 69 показателей, включающих данные анамнеза, клиники, лабораторной и инструментальной диагностики. Создана четырехслойная нейронная сеть: первые два слоя — 69 нейронов, третий слой — 34 нейрона, последний слой — 3 нейрона. Использовано программное обеспечение на языке программирования Java с использованием модуля Encog 3.4.</p></sec><sec><title>Результаты</title><p>Результаты: использование возможностей искусственных нейронных сетей для интеграции в систему поддержки врачебных решений при амбулаторном ведении пациентов с хронической обструктивной болезнью легких показало высокую специфичность.</p></sec><sec><title>Заключение</title><p>Заключение: прогностическая модель реализована в виде компьютерной программы «Программа прогнозирования неблагоприятного исхода, развития сердечно-сосудистых осложнений и эффективности проводимых реабилитационных мероприятий у больных хронической обструктивной болезнью лёгких (CardioRisk)» и внедрена в работу амбулаторно-поликлинических учреждений г. Ростова-на-Дону.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to evaluate the possibility of using artificial neural networks for integration into the medical decision support system as an optimization of outpatient management of patients with COPD.</p></sec><sec><title>Materials and methods</title><p>Materials and methods: a dynamic followup of 150 patients with chronic obstructive pulmonary disease, registered at the dispensary for the underlying disease, who completed the outpatient stage of pulmonary rehabilitation after a moderate exacerbation was carried out. The material of the study was a universal questionnaire of 69 indicators, including anamnesis, clinic, laboratory and instrumental diagnostics. A four-layer neural network has been created: the first two layers — 69 neurons, the third layer — 34 neurons and the last layer — 3 neurons.</p></sec><sec><title>Results</title><p>Results: the software was used in the Java programming language using the Encog 3.4 module.</p></sec><sec><title>Conclusion</title><p>Conclusion: the use of the capabilities of artificial neural networks for integration into the medical decision support system in the outpatient management of patients with chronic obstructive pulmonary disease has shown high specificity. The predictive model is implemented in the form of a computer program: "The program for predicting an unfavorable outcome, the development of cardiovascular complications and the effectiveness of rehabilitation measures in patients with chronic obstructive pulmonary disease (CardioRisk)" and was introduced into the work of outpatient polyclinic institutions in Rostov-on-Don.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая обструктивная болезнь лёгких</kwd><kwd>система поддержки принятия врачебных решений</kwd><kwd>искусственные нейронные сети</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic obstructive pulmonary disease</kwd><kwd>medical decision support system</kwd><kwd>artificial neural networks</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Пульмонология. Национальное руководство. Краткое издание. Под ред. А.Г. Чучалина. 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