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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mvjr</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский вестник Юга России</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Herald of the South of Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2219-8075</issn><issn pub-type="epub">2618-7876</issn><publisher><publisher-name>The Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2219-8075-2023-14-4-122-128</article-id><article-id custom-type="elpub" pub-id-type="custom">mvjr-1781</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>3.2.4 МЕДИЦИНА ТРУДА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OCCUPATIONAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Нейропластичность как основа двигательной реабилитации</article-title><trans-title-group xml:lang="en"><trans-title>Neuroplasticity as the basis of motor rehabilitation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-6245-4987</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Амамчян</surname><given-names>А. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Amamchyan</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ашот Эдуардович Амамчян – к.м.н., доцент кафедры нормальной физиологии</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Ashot E. Amamchyan – Cand. Sci. (Med.), Associate Professor of the Physiology Department</p><p>Rostov-on-Don</p></bio><email xlink:type="simple">amashot2011@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7656-2101</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафиятуллина</surname><given-names>Г. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafiyatullina</surname><given-names>G. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гюзяль Шамилевна Гафиятуллина – д.м.н., профессор, заведующий кафедрой нормальной физиологии</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Guzyal’ Sh. Gafiyatullina – Dr. Sci. (Med.), Professor, Head of the Physiology Department</p><p>Rostov-on-Don</p></bio><email xlink:type="simple">ggsh@aaanet.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ростовский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>09</day><month>11</month><year>2023</year></pub-date><volume>14</volume><issue>4</issue><fpage>122</fpage><lpage>128</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Амамчян А.Э., Гафиятуллина Г.Ш., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Амамчян А.Э., Гафиятуллина Г.Ш.</copyright-holder><copyright-holder xml:lang="en">Amamchyan A.E., Gafiyatullina G.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medicalherald.ru/jour/article/view/1781">https://www.medicalherald.ru/jour/article/view/1781</self-uri><abstract><p>Заболевания нервной системы, которые сопровождаются нарушениями локомоторных реакций, занимают ведущее место среди причин инвалидизации. В этой связи в обзоре проведён анализ данных отечественной и зарубежной литературы, посвящённых современным представлениям о нейрофизиологических механизмах пластичности, выступающих в роли ведущего звена в обеспечении восстановления движений при нейромоторных нарушениях. Особое внимание уделяется организации спинального локомоторного центра как общего конечного пути в реализации двигательной реабилитации, а также управлению локомоторного центра с учётом современных представлений о строении двигательной системы организма. По итогам систематизации данных литературы авторами дается заключение о доказанности нейропластичности спинального локомоторного центра и супраспинальных центров регуляции движений, а также указывается на целесообразность поиска методов активации пластичности центральной нервной системы.</p></abstract><trans-abstract xml:lang="en"><p>Diseases of the nervous system, accompanied by impaired locomotor reactions, occupy a leading place among the causes of disability. In this regard, the review carried out an analysis of national and foreign scientific data devoted to current views about the neurophysiological mechanisms of plasticity and their leading role in ensuring the recovery of movements in neuromotor disorders. Special attention is given both to the organization of the spinal locomotor center as a common final path in the implementation of motor rehabilitation, and to the management of the locomotor center, taking into account modern ideas about the structure of the locomotor body system. Based on the results of systematic literature data, the authors concluded that neuroplasticity of the spinal locomotor center and supraspinal centers of movement regulation is proven, and indicate the expediency of searching for methods which activating the plasticity of the central nervous system.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>реабилитация</kwd><kwd>пластичность</kwd><kwd>локомоторный центр</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rehabilitation</kwd><kwd>plasticity</kwd><kwd>locomotor center</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cifu DX. Braddom's Physical Medicine and Rehabilitation (Sixth Edition). Elsevier; 2021.</mixed-citation><mixed-citation xml:lang="en">Cifu DX. Braddom's Physical Medicine and Rehabilitation (Sixth Edition). Elsevier; 2021.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Барулин А.Е., Курушина О.В., Черноволенко Е.П. Нейрореабилитация при инсульте. Нервные болезни. 2021;(1):72-76. https://doi.org/10.24412/2226-0757-2021-12310</mixed-citation><mixed-citation xml:lang="en">Barulin A.E., Kurushina O.V, Chernovolenk E.P. Neurorehabilitation after stroke. Nervous Diseases. 2021;(1):72-76.(In Russ.). https://doi.org/10.24412/2226-0757-2021-12310</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Maier M, Ballester BR, Verschure PFMJ. Principles of Neurorehabilitation After Stroke Based on Motor Learning and Brain Plasticity Mechanisms. Front Syst Neurosci. 2019;13:74. https://doi.org/10.3389/fnsys.2019.00074</mixed-citation><mixed-citation xml:lang="en">Maier M, Ballester BR, Verschure PFMJ. Principles of Neurorehabilitation After Stroke Based on Motor Learning and Brain Plasticity Mechanisms. Front Syst Neurosci. 2019;13:74. https://doi.org/10.3389/fnsys.2019.00074</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kaczmarek B. Current views on neuroplasticity: what is new and what is old? Acta neuropsychologica. 2020;18(1):1-14. https://doi.org/10.5604/01.3001.0013.8808</mixed-citation><mixed-citation xml:lang="en">Kaczmarek B. Current views on neuroplasticity: what is new and what is old? Acta neuropsychologica. 2020;18(1):1-14. https://doi.org/10.5604/01.3001.0013.8808</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Джеймс У. Психология (Классики мировой психологии). Под ред. Л. А. Петровской. М.: Педагогика; 1991.</mixed-citation><mixed-citation xml:lang="en">Petrovskaya L.A., ed. James W. Psychology (Classics of world psychology). Mosocw: Pedagogy; 1991. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Puderbaugh M., Emmady P.D. Neuroplasticity. Florida: StatPearls Publishing; 2023.</mixed-citation><mixed-citation xml:lang="en">Puderbaugh M., Emmady P.D. Neuroplasticity. Florida: StatPearls Publishing; 2023.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Sherrington C.S. The integrative action of the nervous system. London: New Haven Yale Univ. Press; 1906.</mixed-citation><mixed-citation xml:lang="en">Sherrington C.S. The integrative action of the nervous system. London: New Haven Yale Univ. Press; 1906.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Асратян Э.А. Физиология центральной нервной системы. М.: Изд-во АМН СССР; 1953.</mixed-citation><mixed-citation xml:lang="en">Asratyan E.A. Fiziologiya tsentralnoy nervnoy sistemy. Moscow: Izd-vo AMN SSSR; 1953. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Анохин П. К. Биология и нейрофизиология условного рефлекса. М.: Медицина; 1968.</mixed-citation><mixed-citation xml:lang="en">Anokhin P.K. Biologiya i neyrofiziologiya uslovnogo refleksa. Moscow: Meditsina; 1968. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Bliss TV, Gardner-Medwin AR. Long-lasting potentiation of synaptic transmission in the dentate area of the unanaestetized rabbit following stimulation of the perforant path. J Physiol. 1973;232(2):357-74. https://doi.org/10.1113/jphysiol.1973.sp010274. PMID: 4727085; PMCID: PMC1350459.</mixed-citation><mixed-citation xml:lang="en">Bliss TV, Gardner-Medwin AR. Long-lasting potentiation of synaptic transmission in the dentate area of the unanaestetized rabbit following stimulation of the perforant path. J Physiol. 1973;232(2):357-74. https://doi.org/10.1113/jphysiol.1973.sp010274. PMID: 4727085; PMCID: PMC1350459.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang K, Liu Y, Liu J, Liu R, Cao C. Detecting structural and functional neuroplasticity in elite ice-skating athletes. Hum Mov Sci. 2021;78:102795. https://doi.org/10.1016/j.humov.2021.102795</mixed-citation><mixed-citation xml:lang="en">Zhang K, Liu Y, Liu J, Liu R, Cao C. Detecting structural and functional neuroplasticity in elite ice-skating athletes. Hum Mov Sci. 2021;78:102795. https://doi.org/10.1016/j.humov.2021.102795</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Owji S, Shoja MM. The History of Discovery of Adult Neurogenesis. Clin Anat. 2020;33(1):41-55. doi: 10.1002/ca.23447</mixed-citation><mixed-citation xml:lang="en">Owji S, Shoja MM. The History of Discovery of Adult Neurogenesis. Clin Anat. 2020;33(1):41-55. doi: 10.1002/ca.23447</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Grafman J. Conceptualizing functional neuroplasticity. J Commun Disord. 2000;33(4):345-55; quiz 355-6. https://doi.org/10.1016/s0021-9924(00)00030-7</mixed-citation><mixed-citation xml:lang="en">Grafman J. Conceptualizing functional neuroplasticity. J Commun Disord. 2000;33(4):345-55; quiz 355-6. https://doi.org/10.1016/s0021-9924(00)00030-7</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">La Rosa C, Parolisi R, Bonfanti L. Brain Structural Plasticity: From Adult Neurogenesis to Immature Neurons. Front Neurosci. 2020;14:75. doi: 10.3389/fnins.2020.00075</mixed-citation><mixed-citation xml:lang="en">La Rosa C, Parolisi R, Bonfanti L. Brain Structural Plasticity: From Adult Neurogenesis to Immature Neurons. Front Neurosci. 2020;14:75. doi: 10.3389/fnins.2020.00075</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Andoh M, Koyama R. Microglia regulate synaptic development and plasticity. Dev Neurobiol. 2021;81(5):568-590. https://doi.org/10.1002/dneu.22814</mixed-citation><mixed-citation xml:lang="en">Andoh M, Koyama R. Microglia regulate synaptic development and plasticity. Dev Neurobiol. 2021;81(5):568-590. https://doi.org/10.1002/dneu.22814</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Гафиятуллина Г.Ш., Хананашвили Я.А. Нейропластичность эмбриональной ткани мозга крыс при нарушении гемодинамического обеспечения. Вестник новых медицинских технологий. 2015;22(4):54-63. https://doi.org/10.12737/17025</mixed-citation><mixed-citation xml:lang="en">Gafijatullina G.Sh. Khananashvili Ya.A. Neuroplasticity of embryonic brain tissue in the rats at hemodynamic disturbance. Journal of new medical technologies. 2015;22(4):54-63. (In Russ.). https://doi.org/10.12737/17025</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Ango F, Gallo NB, Van Aelst L. Molecular mechanisms of axo-axonic innervation. Curr Opin Neurobiol. 2021;69:105-112. https://doi.org/10.1016/j.conb.2021.03.002</mixed-citation><mixed-citation xml:lang="en">Ango F, Gallo NB, Van Aelst L. Molecular mechanisms of axo-axonic innervation. Curr Opin Neurobiol. 2021;69:105-112. https://doi.org/10.1016/j.conb.2021.03.002</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Marshall KL, Farah MH. Axonal regeneration and sprouting as a potential therapeutic target for nervous system disorders. Neural Regen Res. 2021;16(10):1901-1910. https://doi.org/10.4103/1673-5374.308077</mixed-citation><mixed-citation xml:lang="en">Marshall KL, Farah MH. Axonal regeneration and sprouting as a potential therapeutic target for nervous system disorders. Neural Regen Res. 2021;16(10):1901-1910. https://doi.org/10.4103/1673-5374.308077</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Nicolini C, Fahnestock M, Gibala MJ, Nelson AJ. Understanding the Neurophysiological and Molecular Mechanisms of Exercise-Induced Neuroplasticity in Cortical and Descending Motor Pathways: Where Do We Stand? Neuroscience. 2021;457:259-282. https://doi.org/10.1016/j.neuroscience.2020.12.013</mixed-citation><mixed-citation xml:lang="en">Nicolini C, Fahnestock M, Gibala MJ, Nelson AJ. Understanding the Neurophysiological and Molecular Mechanisms of Exercise-Induced Neuroplasticity in Cortical and Descending Motor Pathways: Where Do We Stand? Neuroscience. 2021;457:259-282. https://doi.org/10.1016/j.neuroscience.2020.12.013</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Stampanoni Bassi M, Iezzi E, Gilio L, Centonze D, Buttari F. Synaptic Plasticity Shapes Brain Connectivity: Implications for Network Topology. Int J Mol Sci. 2019;20(24):6193. https://doi.org/10.3390/ijms20246193</mixed-citation><mixed-citation xml:lang="en">Stampanoni Bassi M, Iezzi E, Gilio L, Centonze D, Buttari F. Synaptic Plasticity Shapes Brain Connectivity: Implications for Network Topology. Int J Mol Sci. 2019;20(24):6193. https://doi.org/10.3390/ijms20246193</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Зефиров А.Л., Мухамедъяров М.А. Механизмы кратковременных форм синаптической пластичности. Российский физиологический журнал им. И.М Сеченова. 2004;90(8):1041-1059. eLIBRARY ID: 42623183</mixed-citation><mixed-citation xml:lang="en">Zefirov A.L., Mukhamedyarov M.A. Mechanisms of short-term forms of synaptic plasticity. Russian physiological journal. I.M Sechenov. 2004;90(8):1041-1059. (In Russ.). eLIBRARY ID: 42623183</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Fernandes D, Carvalho AL. Mechanisms of homeostatic plasticity in the excitatory synapse. J Neurochem. 2016;139(6):973-996. https://doi.org/10.1111/jnc.13687</mixed-citation><mixed-citation xml:lang="en">Fernandes D, Carvalho AL. Mechanisms of homeostatic plasticity in the excitatory synapse. J Neurochem. 2016;139(6):973-996. https://doi.org/10.1111/jnc.13687</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Abrahamsson T, Chou CYC, Li SY, Mancino A, Costa RP, et al. Differential Regulation of Evoked and Spontaneous Release by Presynaptic NMDA Receptors. Neuron. 2017;96(4):839-855.e5. https://doi.org/10.1016/j.neuron.2017.09.030</mixed-citation><mixed-citation xml:lang="en">Abrahamsson T, Chou CYC, Li SY, Mancino A, Costa RP, et al. Differential Regulation of Evoked and Spontaneous Release by Presynaptic NMDA Receptors. Neuron. 2017;96(4):839-855.e5. https://doi.org/10.1016/j.neuron.2017.09.030</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Mahalakshmi B, Maurya N, Lee SD, Bharath Kumar V. Possible Neuroprotective Mechanisms of Physical Exercise in Neurodegeneration. Int J Mol Sci. 2020;21(16):5895. https://doi.org/10.3390/ijms21165895</mixed-citation><mixed-citation xml:lang="en">Mahalakshmi B, Maurya N, Lee SD, Bharath Kumar V. Possible Neuroprotective Mechanisms of Physical Exercise in Neurodegeneration. Int J Mol Sci. 2020;21(16):5895. https://doi.org/10.3390/ijms21165895</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Hebert C, Behel JM, Pal G, Kasi R, Kompoliti K. Multidisciplinary inpatient rehabilitation for Functional Movement Disorders: A prospective study with long term follow up. Parkinsonism Relat Disord. 2021;82:50-55. https://doi.org/10.1016/j.parkreldis.2020.11.018</mixed-citation><mixed-citation xml:lang="en">Hebert C, Behel JM, Pal G, Kasi R, Kompoliti K. Multidisciplinary inpatient rehabilitation for Functional Movement Disorders: A prospective study with long term follow up. Parkinsonism Relat Disord. 2021;82:50-55. https://doi.org/10.1016/j.parkreldis.2020.11.018</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Сеченов И.М. Физиология нервных центров. Из лекций, читанных в Собрании врачей в Москве в 1889-1890 гг. Под ред. Коштоянца Х.С. М.: Изд-во АМН СССР; 1952.</mixed-citation><mixed-citation xml:lang="en">Koshtoyants KH.S., ed. Sechenov I.M. Fiziologiya nervnykh tsentrov. Iz lektsiy, chitannykh v Sobranii vrachey v Moskve v 1889-1890 gg. Moscow: Izd-vo AMN SSSR; 1952. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Schnerwitzki D, Englert C, Schmidt M. Adapting the pantograph limb: Differential robustness of fore- and hindlimb kinematics against genetically induced perturbation in the neural control networks and its evolutionary implications. Zoology (Jena). 2023;157:126076. https://doi.org/10.1016/j.zool.2023.126076</mixed-citation><mixed-citation xml:lang="en">Schnerwitzki D, Englert C, Schmidt M. Adapting the pantograph limb: Differential robustness of fore- and hindlimb kinematics against genetically induced perturbation in the neural control networks and its evolutionary implications. Zoology (Jena). 2023;157:126076. https://doi.org/10.1016/j.zool.2023.126076</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">McCrea DA, Rybak IA. Organization of mammalian locomotor rhythm and pattern generation. Brain Res Rev. 2008;57(1):134-46. https://doi.org/10.1016/j.brainresrev.2007.08.006</mixed-citation><mixed-citation xml:lang="en">McCrea DA, Rybak IA. Organization of mammalian locomotor rhythm and pattern generation. Brain Res Rev. 2008;57(1):134-46. https://doi.org/10.1016/j.brainresrev.2007.08.006</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Цымбалюк В.И., Медведев В.В. Спинной мозг: элегия надежды. Винница: Нова книга; 2010.</mixed-citation><mixed-citation xml:lang="en">Tsymbalyuk V.I., Medvedev V.V. Spinnoy mozg: elegiya nadezhdy. Vinnitsa: Nova kniga; 2010. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Базиян А.С., Григорян Г.А., Иоффе М.Е. Регуляция двигательного поведения. Успехи физиологических наук. 2011;42(3):65-80. PMID: 21950009.</mixed-citation><mixed-citation xml:lang="en">Bazian AS, Grigir'ian GA, Ioffe ME. [Regulation of motor behaviour]. Usp Fiziol Nauk. 2011;42(3):65-80. (In Russ.) PMID: 21950009.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Kiehn O. Development and functional organization of spinal locomotor circuits. Curr Opin Neurobiol. 2011;21(1):100-9. https://doi.org/10.1016/j.conb.2010.09.004</mixed-citation><mixed-citation xml:lang="en">Kiehn O. Development and functional organization of spinal locomotor circuits. Curr Opin Neurobiol. 2011;21(1):100-9. https://doi.org/10.1016/j.conb.2010.09.004</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Edgerton VR, Courtine G, Gerasimenko YP, Lavrov I, Ichiyama RM, et al. Training locomotor networks. Brain Res Rev. 2008;57(1):241-54. https://doi.org/10.1016/j.brainresrev.2007.09.002</mixed-citation><mixed-citation xml:lang="en">Edgerton VR, Courtine G, Gerasimenko YP, Lavrov I, Ichiyama RM, et al. Training locomotor networks. Brain Res Rev. 2008;57(1):241-54. https://doi.org/10.1016/j.brainresrev.2007.09.002</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Городничев Р.М., Пухов А.М., Моисеев С.А., Иванов С.М., Маркевич В.В., и др. Регуляция фаз шагательного цикла при неинвазивной электрической стимуляции спинного мозга. Физиология человека. 2021;47(1):73-83. https://doi.org/10.1134/S0362119721010059</mixed-citation><mixed-citation xml:lang="en">Gorodnichev R.M., Pukhov A.M., Moiseev, S.A., Ivanov S.M., Markevich V.V., et al. Regulation of gait cycle phases during noninvasive electrical stimulation of the spinal cord. Hum Physiol. 2021;47(1):60–69. (In Russ.) https://doi.org/10.1134/S0362119721010059</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Григорян А.К. Амамчян А.Э. Принципы нейрореабилитации - взгляд клинициста и физиолога. Синергия наук. 2019;32:1033-1059. eLIBRARY ID: 37037123</mixed-citation><mixed-citation xml:lang="en">Grigoryan A.K. Amamchyan A.E. Principles of neurorehabilitation - the view of a clinician and physiologist. Synergy of Sciences. 2019;32:1033-1059. (In Russ.) eLIBRARY ID: 37037123</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Takakusaki K. Functional Neuroanatomy for Posture and Gait Control. J Mov Disord. 2017;10(1):1-17. https://doi.org/10.14802/jmd.16062</mixed-citation><mixed-citation xml:lang="en">Takakusaki K. Functional Neuroanatomy for Posture and Gait Control. J Mov Disord. 2017;10(1):1-17. https://doi.org/10.14802/jmd.16062</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Котенко К.В., Епифанов В.А., Епифанов А.В. Реабилитация при заболеваниях и повреждениях нервной системы. М: ГЭОТАР-Медиа, 2016.</mixed-citation><mixed-citation xml:lang="en">Kotenko K.V., Yepifanov V.A., Yepifanov A.V. Reabilitatsiya pri zabolevaniyakh i povrezhdeniyakh nervnoy sistemy. M: GEOTAR-Media, 2016. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Huo CC, Zheng Y, Lu WW, Zhang TY, Wang DF, et al. Prospects for intelligent rehabilitation techniques to treat motor dysfunction. Neural Regen Res. 2021;16(2):264-269. https://doi.org/10.4103/1673-5374.290884</mixed-citation><mixed-citation xml:lang="en">Huo CC, Zheng Y, Lu WW, Zhang TY, Wang DF, et al. Prospects for intelligent rehabilitation techniques to treat motor dysfunction. Neural Regen Res. 2021;16(2):264-269. https://doi.org/10.4103/1673-5374.290884</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
