mvjrМедицинский вестник Юга РоссииMedical Herald of the South of Russia2219-80752618-7876The Rostov State Medical University10.21886/2219-8075-2022-13-3-173-182mvjr-1636Research ArticleВНУТРЕННИЕ БОЛЕЗНИINTERNAL DISEASESПрофиль коморбидных состояний и структура смертности пациентов с ревматоидным артритом в Ставропольском крае: предварительные результатыThe profile of comorbid conditions and the structure of mortality in patients with rheumatoid arthritis in the Stavropol Territory: preliminary resultshttps://orcid.org/0000-0002-2386-355XЩендригинИ. Н.ShchendriginI. N.

Щендригин Иван Николаевич - кандидат медицинских наук, главный врач.

Ставрополь.

Ivan N. Shchendrigin - Cand. Sci. (Med.), Chief Physician, Stavropol Regional Clinical Hospital.

Stavropol.

rhstav@yandex.ruhttps://orcid.org/0000-0002-7923-5413МажаровВ. Н.MazharovV. N.

Мажаров Виктор Николаевич – кандидат медицинских наук, ректор СтГМУ МЗ РФ.

Ставрополь.

Viktor N. Mazharov - Cand. Sci. (Med.), Rector, State Medical University.

Stavropol.

postmaster@stgmu.ruСтавропольская краевая клиническая больницаРоссияStavropol Regional Clinical HospitalRussian FederationСтавропольский государственный медицинский университетРоссияState Medical UniversityRussian Federation202230092022133173182Copyright © Щендригин И.Н., Мажаров В.Н., 20222022Щендригин И.Н., Мажаров В.Н.Shchendrigin I.N., Mazharov V.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.medicalherald.ru/jour/article/view/1636

Цель: изучение коморбидного фона и структуры смертности больных ревматоидным артритом (РА) в Ставропольском крае в когорте пациентов Ставропольской краевой клинической больницы (СККБ) в период 2015–2021 гг. Материалы и методы: проведён систематизированный обзор литературы. Выполнен анализ протоколов вскрытий патологоанатомического отделения СККБ за 2015-2021 гг. Изучены компонент коморбидности и летальные исходы пациентов с РА в патологоанатомическом диагнозе. Результаты: структура коморбидной патологии больных РА в когорте пациентов СККБ включала ишемическую болезнь сердца (ИБС), аутоиммунный тиреоидит (АТ), респираторные заболевания (РЗ), гипертоническую болезнь (ГБ), «Бластоматоз», сахарный диабет (СД), инфекцию СOVID-19. Профиль коморбидности пациентов с РА в порядке уменьшения частоты встречаемости патологического состояния имел следующий вид: ИБС (35,29%) > РЗ (29,41%) > («Бластоматоз», СOVID-19 по 11,75%) > (АТ, ГБ, СД по 5,88%). Структура состояний, привёдших к летальному исходу пациентов с РА, включала острый инфаркт миокарда (40,0%), геморрагический инсульт (6,67%), рак молочной железы (13,33%), рак щитовидной железы (6,67%), вирусная пневмония (20,0%), сепсис (13,33%). Выводы: полученные данные несут информацию, которая может быть использована ревматологами для оптимизации стратегии управления РА и риском коморбидных состояний.

Objective: to study the comorbid background and mortality structure of patients with rheumatoid arthritis (RA) in the Stavropol region in a cohort of patients of the Stavropol Regional Clinical Hospital (SRCH) within the period 2015–2021. Materials and methods: There was carried out systematic review of the literature. There was carried out the analysis of the protocols of autopsies in the pathoanatomical department of the SRCH within 2015-2021. There were studied the comorbidity component and lethal outcomes of patients with RA in the pathoanatomical diagnosis. Results: the structure of the comorbid pathology of RA patients in the SRCH cohort included coronary heart disease (CHD), autoimmune thyroiditis (AT), respiratory diseases (RD), hypertension (HT), “Blastomatosis”, diabetes mellitus (DM), COVID-19 infection. The comorbidity profile of patients with RA in decreasing order of the incidence of the pathological condition was as follows: CHD (35.29%) > RD (29.41%) > (“Blastomatosis”, СOVID-19 by 11.75%) > (AT, HT, DM by 5.88%). The structure of the conditions that led to the death of patients with RA included: acute myocardial infarction (40.0%), hemorrhagic stroke (6.67%), breast cancer (13.33%), thyroid cancer (6.67%), viral pneumonia (20.0%), sepsis (13.33%). Conclusions: the data obtained provide information that can be used by rheumatologists to optimize the strategy for managing RA and the risk of comorbid conditions.

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The authors declare that there are no conflicts of interest present.