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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mvjr</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский вестник Юга России</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Herald of the South of Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2219-8075</issn><issn pub-type="epub">2618-7876</issn><publisher><publisher-name>The Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2219-8075-2022-13-2-162-167</article-id><article-id custom-type="elpub" pub-id-type="custom">mvjr-1569</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭНДОКРИНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ENDOCRYNOLOGY</subject></subj-group></article-categories><title-group><article-title>Современные подходы к ведению гендерной дисфории с позиции эндокринолога: клиническое наблюдение</article-title><trans-title-group xml:lang="en"><trans-title>Modern approaches to the management of gender dysphoria from endocrinologist`s viewpoint: clinical case</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4874-7835</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волкова</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Volkova</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Наталья Ивановна Волкова, д. м. н., проф., заведующая кафедрой внутренних болезней №3 </p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Natalya I. Volkova, Dr. Sci. (Med.), Professor, head of Department of internal diseases №3 </p><p>Rostov-on-Don</p></bio><email xlink:type="simple">n_i_volkova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8690-681X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Давиденко</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Davidenko</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Илья Юрьевич Давиденко, к. м. н., доцент кафедры внутренних болезней №3 </p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Ilya Y. Davidenko, Cand. Sci. (Med.), associate professor of Department of internal medicine, №3 </p><p>Rostov-on-Don</p></bio><email xlink:type="simple">davidenko.iu@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5838-4383</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дегтярева</surname><given-names>Ю. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Degtyareva</surname><given-names>Yu. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлия Сергеевна Дегтярева, аспирант кафедры внутренних болезней №3</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>Yuliya S. Degtyareva, postgraduate student of Department of internal diseases №3 </p><p>Rostov-on-Don</p></bio><email xlink:type="simple">shitova.julia@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ростовский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>06</day><month>07</month><year>2022</year></pub-date><volume>13</volume><issue>2</issue><fpage>162</fpage><lpage>167</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Волкова Н.И., Давиденко И.Ю., Дегтярева Ю.С., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Волкова Н.И., Давиденко И.Ю., Дегтярева Ю.С.</copyright-holder><copyright-holder xml:lang="en">Volkova N.I., Davidenko I.Y., Degtyareva Y.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medicalherald.ru/jour/article/view/1569">https://www.medicalherald.ru/jour/article/view/1569</self-uri><abstract><p>Оказание медицинской помощи по коррекции пола людям с гендерной дисфорией - сложная мультидисциплинарная задача, успех в решении которой определяется тесным сотрудничеством специалистов, квалифицированных в вопросах помощи таким пациентам, таких как психиатр, эндокринолог и хирург. Помимо диагностического обследования пациентам с гендерной дисфорией требуется психотерапия или психологическое консультирование, заместительная гормональная терапия и, при необходимости, хирургическая коррекция пола. Перед назначением гормональной терапии необходимо убедиться, что пациент соответствует критериям диагноза гендерной дисфории, быть уверенным, что желание пациента изменить пол оправдано, все последствия терапии, включая возможные физические изменения и сроки их возникновения, разъяснены. Хирургические вмешательства на гениталиях возможны только после как минимум одного года гормонотерапии и жизни в роли выбранного гендера. Разработанные на сегодняшний день алгоритмы медицинской помощи для лиц с гендерной дисфорией детально описывают механизм коррекции пола, вклад различных специалистов в данный процесс, а также возможные риски и методы их предотвращения. Только тщательное соблюдение этапов диагностики и лечения без нарушения их последовательности может привести к успешному достижению конечного результата. В то время как любые отступления от алгоритмов, ввиду объективных и субъективных причин, влекут за собой серьезные жизнеугрожающие последствия, что наглядно продемонстрировано в клинических случаях, представленных в данной статье.</p></abstract><trans-abstract xml:lang="en"><p>Providing medical care to people with gender dysphoria is a complex multidisciplinary task, the success of which is determined by the close cooperation of specialists qualified in helping such patients, such as a psychiatrist, endocrinologist, and surgeon. In addition to diagnostic testing, patients with gender dysphoria require psychotherapy or psychological counseling, hormone replacement therapy, and, if necessary, gender confirmation surgery. Before prescribing hormone therapy, it is necessary to make sure that the patient meets the criteria for the diagnosis of gender dysphoria, to be sure that the patient’s desire to change gender is justified, all the consequences of therapy, including possible physical changes and the timing of their occurrence, are explained. Genital reconstruction procedures are possible only after at least one year of hormone therapy and life in the role of the chosen gender. The algorithms of medical care for persons with gender dysphoria developed to date describe in detail the mechanism of gender reassignment, the contribution of various specialists to this process, as well as possible risks and methods for their prevention. Only careful observance of the stages of diagnosis and treatment without violating their sequence can lead to the successful achievement of the result. while any deviations from the algorithms, due to objective and subjective reasons, entail serious life-threatening consequences, which is clearly demonstrated in the clinical cases presented in this article.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гендерная дисфория</kwd><kwd>гормональная терапия</kwd><kwd>клиничеcкий случай</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gender dysphoria</kwd><kwd>transgender</kwd><kwd>hormone therapy</kwd><kwd>case report</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">The World Professional Association for Transgender Health (WPATH). Standards of Care [Internet]. wPATH; 2017. Available from: https://www.wpath.org/publications/soc/. 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