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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mvjr</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский вестник Юга России</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Herald of the South of Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2219-8075</issn><issn pub-type="epub">2618-7876</issn><publisher><publisher-name>The Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2219-8075-2021-12-4-62-66</article-id><article-id custom-type="elpub" pub-id-type="custom">mvjr-1458</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>3.1.20 КАРДИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>Манифестация электрокардиографических признаков синдрома Бругада на фоне терапии антиаритмическим препаратом Iс класса Этацизином</article-title><trans-title-group xml:lang="en"><trans-title>Manifestation of electrocardiographic signs of the Brugadа syndrome in the setting of therapy with class Ic antiarrhythmic drug Ethacizine</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5408-7250</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сазонова</surname><given-names>Ю. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sazonova</surname><given-names>Yu. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сазонова Юлия Николаевна, врач функциональной диагностики</p><p>Ростов-на-Дону</p><p> </p></bio><bio xml:lang="en"><p>Yuliуa N. Sazonova, functional diagnostician</p><p>Rostov-on-Don</p></bio><email xlink:type="simple">julya.zu@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Лечебно-реабилитационный центр №1</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Treatment and rehabilitation center No.1</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>25</day><month>12</month><year>2021</year></pub-date><volume>12</volume><issue>4</issue><fpage>62</fpage><lpage>66</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сазонова Ю.Н., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Сазонова Ю.Н.</copyright-holder><copyright-holder xml:lang="en">Sazonova Y.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medicalherald.ru/jour/article/view/1458">https://www.medicalherald.ru/jour/article/view/1458</self-uri><abstract><p>Представлено клиническое наблюдение пациента с манифестированным синдромом Бругада на фоне лечения антиаритмическим препаратом Iс класса этацизином. Особенностью этого случая является полное исчезновение ЭКГ-признаков синдрома Бругада и нормализация ЭКГ после отмены препарата. Врачу функциональной диагностики важно своевременно обращать внимание на Бругада-паттерн ЭКГ и рассматривать подобные изменения не только в связи с субэпикардиальной ишемией и возможным повреждением миокарда.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>The article presents a clinical case of a patient presenting with electrocardiographic signs of the Brugada syndrome in the setting of therapy with class Ic antiarrhythmic drug Ethacizine. The special feature of this case is a complete disappearance of ECG signs of the Brugada syndrome and the normalization of ECG after withdrawal of the drug. For a functional diagnostiсian, it is important to pay timely attention to the Brugada pattern on the ECG and consider such changes not only in connection with subepicardial ischemia and possible myocardial damage.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром Бругада</kwd><kwd>желудочковая экстрасистолия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rugadа syndrome</kwd><kwd>ventricular extrasystolia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ikeda T. Brugada syndrome: current clinical aspects and risk stratification. Ann Noninvasive Electrocardiol. 2002; 7(3):251-62. DOI: 10.1111/j.1542-474x.2002.tb00172.x.</mixed-citation><mixed-citation xml:lang="en">Ikeda T. Brugada syndrome: current clinical aspects and risk stratification. Ann Noninvasive Electrocardiol. 2002; 7(3):251- 62. DOI: 10.1111/j.1542-474x.2002.tb00172.x.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Junttila MJ, Gonzalez M, Lizotte E, Benito B, Vernooy K, et al. Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias. Circulation. 2008; 117(14):1890- 3. DOI: 10.1161/CIRCULATIONAHA.107.746495.</mixed-citation><mixed-citation xml:lang="en">Junttila MJ, Gonzalez M, Lizotte E, Benito B, Vernooy K, et al. Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias. Circulation. 2008; 117(14):1890-3. DOI: 10.1161/CIRCULATIONAHA.107.746495.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Макаров Л.М., Комолятова В.Н. Появление электрокардиографических признаков синдрома Бругада на фоне терапии антиаритмическим препаратом IС класса Этацизином. Кардиология. 2011; 51(4):93-95. eLIBRARY ID: 16606257</mixed-citation><mixed-citation xml:lang="en">Makarov L.M., Komolyatova V.N. Appearance of ECG signs of the Brugada syndrome during therapy with class 1C antiarrhythmic drug Ethacizine. Kardiologiia. 2011; 51(4):93-95. (In Russ.). eLIBRARY ID: 16606257</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
