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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mvjr</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский вестник Юга России</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Herald of the South of Russia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2219-8075</issn><issn pub-type="epub">2618-7876</issn><publisher><publisher-name>The Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">mvjr-1214</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Анализ течения беременности, родов и перинатальных исходов у женщин, страдающих гепатитом С</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of Pregnancy, Labor and Perinatal Outcomes of Women with Hepatitis C</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рымашевский</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Rymashevsky</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра акушерства и гинекологии №1</p><p>344022, г. Ростов-на-Дону, пер. Нахичеванский, 29</p></bio><bio xml:lang="en"><p>Department of Obstetrics and Gynecology № 1</p><p>29 Nakhichevansky st., Rostov-on-Don, 344022</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волков</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Volkov</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра акушерства и гинекологии №1</p><p>344022, г. Ростов-на-Дону, пер. Нахичеванский, 29</p></bio><bio xml:lang="en"><p>Department of Obstetrics and Gynecology № 1</p><p>29 Nakhichevansky st., Rostov-on-Don, 344022</p></bio><email xlink:type="simple">avolkov@aaanet.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терехина</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Terekhina</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра акушерства и гинекологии №1</p><p>344022, г. Ростов-на-Дону, пер. Нахичеванский, 29</p></bio><bio xml:lang="en"><p>Department of Obstetrics and Gynecology № 1</p><p>29 Nakhichevansky st., Rostov-on-Don, 344022</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ковалева</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovaleva</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра акушерства и гинекологии №1</p><p>344022, г. Ростов-на-Дону, пер. Нахичеванский, 29</p></bio><bio xml:lang="en"><p>Department of Obstetrics and Gynecology № 1</p><p>29 Nakhichevansky st., Rostov-on-Don, 344022</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Уелина</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Uelina</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра акушерства и гинекологии №1</p><p>344022, г. Ростов-на-Дону, пер. Нахичеванский, 29</p></bio><bio xml:lang="en"><p>Department of Obstetrics and Gynecology № 1</p><p>29 Nakhichevansky st., Rostov-on-Don, 344022</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ростовский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2011</year></pub-date><volume>0</volume><issue>2</issue><fpage>102</fpage><lpage>105</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рымашевский А.Н., Волков А.Е., Терехина Л.А., Ковалева Э.А., Уелина Г.А., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Рымашевский А.Н., Волков А.Е., Терехина Л.А., Ковалева Э.А., Уелина Г.А.</copyright-holder><copyright-holder xml:lang="en">Rymashevsky A.N., Volkov A.E., Terekhina L.A., Kovaleva E.A., Uelina G.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medicalherald.ru/jour/article/view/1214">https://www.medicalherald.ru/jour/article/view/1214</self-uri><abstract><sec><title>Цель</title><p>Цель: оценка влияния инфицирования вирусным гепатитом С (ВГС) на течение беременности, родов и состояние новорожденных.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы: обследовано 49 беременных, страдающих ВГС (основная группа). Группу сравнения составили 124 «практически здоровые» женщины с физиологическим течением беременности. В группах оценивали паритет, клинико-лабораторные показатели крови (общий анализ крови, гематокрит, лейкоцитарный индекс интоксикации), течение беременности, родов, состояние новорожденных детей и их заболеваемость.</p></sec><sec><title>Результаты</title><p>Результаты: беременность при ВГС протекает с высокой частотой развития фетоплацентарной недостаточности (практически в 2 раза чаще, чем в группе контроля, p &lt; 0,05). Влияние ВГС на течение родов не выявлено: роды протекали в большинстве случаев так же, как и в группе сравнения. Однако при практически равных объемах кровопотери в группах частота послеродовой анемии у родильниц, инфицированных ВГС, наблюдалась достоверно чаще (p &lt; 0,05). Структура перинатальной патологии новорожденных у женщин, инфицированных ВГС, представлена в основном замедлением роста и недостаточностью питания плода и расстройствами, связанными с укорочением срока беременности и малой массой тела при рождении.</p></sec><sec><title>Заключение</title><p>Заключение: ВГС является фактором, влияющим на течение беременности, но не влияющим на развитие перинатальной патологии у новорожденных.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose: Estimate the influence of infection with hepatitis C virus (HCV) on pregnancy, childbirth and neonatal status.</p></sec><sec><title>Materials and Methods</title><p>Materials and Methods: Examined 49 pregnant women with HCV (core group). Comparison group consisted of 124 apparently healthy women with physiological pregnancy. In the groups evaluated parity, clinical and laboratory parameters of blood (blood count, hematocrit, leukocyte index of intoxication), during pregnancy, birth, state of newborn babies and their incidence.</p></sec><sec><title>Results</title><p>Results: Pregnancy with HCV occurs with a high incidence of placental insufficiency (almost 2 times more frequently than in the control group, p &lt; 0,05). Effect of HCV on the course of childbirth is not revealed: progress of labor in most cases the same way as in the comparison group. However, in almost equal amounts of blood loss in groups the frequency of postpartum anemia in parturients infected with HCV, we observed significantly more frequently (p &lt; 0,05). The structure of perinatal pathology in infants of women infected with HCV, represented mainly by slowing growth and fetal malnutrition and disorders related to shortening the duration of pregnancy and low birth weight.</p></sec><sec><title>Summary</title><p>Summary: HCV is a factor influencing the course of pregnancy, but does not affect the development of perinatal pathology in infants.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>гепатит С</kwd><kwd>беременность</kwd><kwd>роды</kwd><kwd>перинатальные исходы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hepatitis C</kwd><kwd>pregnancy</kwd><kwd>childbirth</kwd><kwd>perinatal outcomes</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Jones J.S., Dieterich D.T. Treatment of hepatitis C virus and HIV coinfection: the road less traveled // AIDS Read. – 2001. – V.11, №10. – P.505-510.</mixed-citation><mixed-citation xml:lang="en">Jones J.S., Dieterich D.T. Treatment of hepatitis C virus and HIV coinfection: the road less traveled // AIDS Read. – 2001. – V.11, №10. – P.505-510.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Alric L., Costedoat N., Piette J.C. Hepatitis C and pregnancy // Rev. Med. Interne – 2002. – V.23, №3. – P.283-291.</mixed-citation><mixed-citation xml:lang="en">Alric L., Costedoat N., Piette J.C. Hepatitis C and pregnancy // Rev. Med. Interne – 2002. – V.23, №3. – P.283-291.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Ищук Н.Д., Кузьмин В.Н. Вирусный гепатит С и беременность // Терапевтический архив. – 2000. – Т.72. - №10. – С.46-49.</mixed-citation><mixed-citation xml:lang="en">Ищук Н.Д., Кузьмин В.Н. Вирусный гепатит С и беременность // Терапевтический архив. – 2000. – Т.72. - №10. – С.46-49.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Conte D., Colucci A., Minola E. et al. Clinical course of pregnant women with chronic hepatitis C virus infection and risk of mother-to-child hepatitis C virus transmission// Dig. Liver Dis. – 2001. – V.33, № 4. – P.366-371.</mixed-citation><mixed-citation xml:lang="en">Conte D., Colucci A., Minola E. et al. Clinical course of pregnant women with chronic hepatitis C virus infection and risk of mother-to-child hepatitis C virus transmission// Dig. Liver Dis. – 2001. – V.33, № 4. – P.366-371.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Chen J.D., Chung J.L., Kao J.H. Post-partum acute exacerbation of chronic hepatitis in a hepatitis C-carrier mother // J. Gastroenterol. Hepatol. – 2001. – V.16, № 6. – P.705-708.</mixed-citation><mixed-citation xml:lang="en">Chen J.D., Chung J.L., Kao J.H. Post-partum acute exacerbation of chronic hepatitis in a hepatitis C-carrier mother // J. Gastroenterol. Hepatol. – 2001. – V.16, № 6. – P.705-708.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Nordbo S.A., Johansen O.J., Brubakk A.M. Vertical transmission of hepatitis C virus in Sor-Trondelag // Tidsskr. Nor. Laegeforen. – 2002. – V.122, № 20. – P.1977-1980.</mixed-citation><mixed-citation xml:lang="en">Nordbo S.A., Johansen O.J., Brubakk A.M. Vertical transmission of hepatitis C virus in Sor-Trondelag // Tidsskr. Nor. Laegeforen. – 2002. – V.122, № 20. – P.1977-1980.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Roberts E.A., Yeung L. Maternal-infant transmission of hepatitis C virus infection // Hepatology – 2002. – V.36, № 1. – P.106-113.</mixed-citation><mixed-citation xml:lang="en">Roberts E.A., Yeung L. Maternal-infant transmission of hepatitis C virus infection // Hepatology – 2002. – V.36, № 1. – P.106-113.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Paternoster D.M., Fabris F., Palu G. Intra-hepatic cholestasis of pregnancy in hepatitis C virus infection // Acta. Obstet. Gynecol. Scand. – 2002. – V.81, № 2. P.99-103.</mixed-citation><mixed-citation xml:lang="en">Paternoster D.M., Fabris F., Palu G. Intra-hepatic cholestasis of pregnancy in hepatitis C virus infection // Acta. Obstet. Gynecol. Scand. – 2002. – V.81, № 2. P.99-103.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Njouom R., Pasquier C., Ayouba A. Hepatitis C virus infection among pregnant women in Yaounde, Cameroon: prevalence, viremia, and genotypes // J. Med. Virol. – 2003. – V.69, № 3. – P.384-390.</mixed-citation><mixed-citation xml:lang="en">Njouom R., Pasquier C., Ayouba A. Hepatitis C virus infection among pregnant women in Yaounde, Cameroon: prevalence, viremia, and genotypes // J. Med. Virol. – 2003. – V.69, № 3. – P.384-390.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Nie Q., Wang P., Zhou Y. Quantitation of hepatitis C virus RNA in amniotic fluid of gravida infected by hepatitis C virus // Zhonghua Fu Chan Ke Za Zhi – 2002. – V.37, № 1. – P.19-21.</mixed-citation><mixed-citation xml:lang="en">Nie Q., Wang P., Zhou Y. Quantitation of hepatitis C virus RNA in amniotic fluid of gravida infected by hepatitis C virus // Zhonghua Fu Chan Ke Za Zhi – 2002. – V.37, № 1. – P.19-21.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
