mvjrМедицинский вестник Юга РоссииMedical Herald of the South of Russia2219-80752618-7876The Rostov State Medical Universitymvjr-1172Research ArticleОБЗОРЫREVIEWФакторы прогноза при ревматоидном артрите: современное состояние проблемыPrognostic factors in patients with rheumatoid arthritis: current stage of a problemОранскийС. П.OranskiyS. P.

кафедра факультетской терапии

350000, г. Краснодар, ул. Седина, 4

Division of Faculty Therapeutics

7 Sedina st., Krasnodar, 350000

s_oransky@inbox.ruЕлисееваЛ. Н.YeliseyevaL. N.

кафедра факультетской терапии

350000, г. Краснодар, ул. Седина, 4

Division of Faculty Therapeutics

7 Sedina st., Krasnodar, 350000

ХанферянР. А.KhanferyanR. A.

кафедра факультетской терапии

350000, г. Краснодар, ул. Седина, 4

Division of Faculty Therapeutics

7 Sedina st., Krasnodar, 350000

МалхасянИ. Г.MalhasyanI. G.

кафедра факультетской терапии

350000, г. Краснодар, ул. Седина, 4

Division of Faculty Therapeutics

7 Sedina st., Krasnodar, 350000

Кубанский государственный медицинский университетРоссияKuban State Medical UniversityRussian Federation201130032011011822Copyright © Оранский С.П., Елисеева Л.Н., Ханферян Р.А., Малхасян И.Г., 20112011Оранский С.П., Елисеева Л.Н., Ханферян Р.А., Малхасян И.Г.Oranskiy S.P., Yeliseyeva L.N., Khanferyan R.A., Malhasyan I.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.medicalherald.ru/jour/article/view/1172

В последние годы пересмотрены основные подходы к диагностике и лечению ревматоидного артрита (РА). В современных клинических рекомендациях установлены более ранние показания для проведения ранней агрессивной терапии биологическими агентами (БА), в то же время популяция больных с РА неоднородна, имеются различные варианты течения заболевания. В обзоре рассматриваются современные представления о различных прогностических факторах (клинических, иммунологических, рентгенологических, генетических) при РА, применяющихся для оценки динамики заболевания, в том числе на фоне терапии БА.

The basic principles of the diagnostic and treatment of patients with rheumatoid arthritis (RA) has changed in recent years. Last clinical guidelines recommended the initiation of therapy with biologic agents (BA) as early as it possible, however the patient population with RA has heterogeneity of clinical progression. In present review authors analyzed the basic prognostic factors (clinical, immunological, radiological, genetic) that can predict clinical outcomes also in patients with BA therapy.

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The authors declare that there are no conflicts of interest present.