mvjrМедицинский вестник Юга РоссииMedical Herald of the South of Russia2219-80752618-7876The Rostov State Medical Universitymvjr-1170Research ArticleОБЗОРЫREVIEWСклеродермия: особенности течения и возможности лечения. Обзор литературыScleroderma: features of the current and possibility treatments. Review referencesГурскийГ. Э.GurskyG. E.

кафедра кожных и венерических болезней

344022, г. Ростов-на-Дону, пер. Нахичеванский, 29

Department of Skin and Venereal Diseases

29 Nakhichevansky st., Rostov-on-Don, 344022

kenho@mail.ruГребенниковВ. А.GrebennikovV. A.

кафедра кожных и венерических болезней

344022, г. Ростов-на-Дону, пер. Нахичеванский, 29

Department of Skin and Venereal Diseases

29 Nakhichevansky st., Rostov-on-Don, 344022

kenho@mail.ruХоронькоВ. В.HoronkoV. V.

кафедра фармакологии и клинической фармакологии

Department of Pharmacology and Clinical Pharmacology

29 Nakhichevansky st., Rostov-on-Don, 344022

kenho@mail.ruРостовский государственный медицинский университетРоссияRostov State Medical UniversityRussian Federation2011300320110149Copyright © Гурский Г.Э., Гребенников В.А., Хоронько В.В., 20112011Гурский Г.Э., Гребенников В.А., Хоронько В.В.Gursky G.E., Grebennikov V.A., Horonko V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.medicalherald.ru/jour/article/view/1170

Представлены данные из различных литературных источников об особенностях течения ограниченной склеродермии (ОС). Обсуждается гипотеза – ОС и системная склеродермия (ССД) представляют собой разновидности одного патологического процесса, что подтверждается однонаправленностью метаболических сдвигов, общностью патогистологических изменений кожи при обеих формах болезни, а также случаями трансформации локализованного процесса в прогрессирующий системный склероз. Обсуждается частота встречаемости, преобладание тех или иных форм ОС, длительность жизни больных, клинические проявления и длительность течения ОС и ее связь с другими патологическими процессами. Рассматриваются различные схемы лечения ОС, которые носят многокурсовой и многокомпонентный характер.

Data from various references about features of a current limited склеродермии (OS) is presented interfaced. The hypothesis that OS and system scleroderma (SSD) represent versions of one pathological process that proves to be true presence an one-orientation of metabolic shifts, a generality skin changes at both forms of illness, and also cases of transformation of the localised process in a progressing system sclerosis Is discussed. Frequency of occurrence, prevalence of those or other forms of OS, longevity of patients, clinical displays and duration of a current of OS and its communication with other pathological processes is discussed. Various schemes of treatment of OS which have multicourse and multicomponent character are considered.

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The authors declare that there are no conflicts of interest present.